Asceptic necrosis of bone in a dog.

Necrosis of intramedullary bone and bone marrow elements is reported in the long bones of a dog. Radiographically lesions were evident as an irregular increase in intramedullary density. On gross postmortem examination necrotic tissue appeared as yellow-white deposits on the endosteal surface and in the medullary cavity. Microscopically, necrotic bone had empty lacunae and was often covered by basophilic, woven bone. The cause and pathogenesisof aseptic necrosis of bone are discussed.