Literature DB >> 17422592

Moldy sweet clover (dicoumarol) poisoning in Saskatchewan cattle.

B R Blakley.   

Abstract

Information pertaining to 286 animals from 56 herds affected by moldy sweet clover poisoning in Saskatchewan during 1983 was tabulated from the toxicology laboratory records. The morbidity in the affected herds was 12.1%, with a case fatality of 65.5%. Aborted fetuses and calves less than two weeks of age were affected with sweet clover poisoning most often. Sweet clover poisoning was more common during the period from January to April, 91.6% of the morbid animals were seen at this time. The rates of poisoning in beef and dairy cattle were estimated to be 0.156 and 0.095 cases per 1000 cattle respectively. Sweet clover poisoning was observed with the use of large of small bales of sweet clover in 78.9% of the affected herds. The geographical distribution of sweet clover poisoning in Saskatchewan followed the northern regions of the dark brown soil zone and the southern regions of the black soil zone which extend from the mid northwest portion of the province to the extreme southeast region.Dicoumarol concentrations were determined on a variety of tissues including liver, plasma, serum, kidney and muscle. Significant differences in the liver dicoumarol concentrations were found between animals of different ages (P = 0.045). Livers from younger animals, in particular, the fetus, contained lower concentrations of dicoumarol.

Entities:  

Year:  1985        PMID: 17422592      PMCID: PMC1680139     

Source DB:  PubMed          Journal:  Can Vet J        ISSN: 0008-5286            Impact factor:   1.008


  7 in total

1.  PAPER CHROMATOGRAPHIC DETERMINATION OF DICOUMAROL IN BIOLOGICAL MATERIALS.

Authors:  F CHRISTENSEN
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1964

2.  Sweet clover poisoning in newborn calves.

Authors:  C M FRASER; J NELSON
Journal:  J Am Vet Med Assoc       Date:  1959-09-01       Impact factor: 1.936

3.  Comparative pharmacokinetics of coumarin anticoagulants. I. Unusual interaction of bishydroxycoumarin with plasma proteins--development of a new assay.

Authors:  R Nagashima; G Levy; E Nelson
Journal:  J Pharm Sci       Date:  1968-01       Impact factor: 3.534

4.  Moldy sweetclover poisoning in a horse.

Authors:  G K McDonald
Journal:  Can Vet J       Date:  1980-09       Impact factor: 1.008

5.  Sweet clover production and agronomy.

Authors:  B P Goplen
Journal:  Can Vet J       Date:  1980-05       Impact factor: 1.008

6.  Occurrence and range of dicumarol concentrations in sweet clover.

Authors:  M E Benson; H H Casper; L J Johnson
Journal:  Am J Vet Res       Date:  1981-11       Impact factor: 1.156

7.  Moldy sweetclover poisoning in cattle.

Authors:  O M Radostits; G P Searcy; K G Mitchall
Journal:  Can Vet J       Date:  1980-05       Impact factor: 1.008

  7 in total

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