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Literature DB >> 17422242

Examination of the origin of increased equine serum alkaline phosphatase concentrations.

Abstract

Serum alkaline phosphatase activity was found to be increased in 32.6% of equine samples analyzed at the Ontario Veterinary College over an 18 month period. An attempt was made using sensitivity to L-phenylalanine and heat to identify the origin of increased serum alkaline phosphatase isoenzymes present in 44 clinical cases. No difference in sensitivity to either procedure was observed for serum alkaline phosphatase from groups of foals and horses representing different clinical problems. Alkaline phosphatase of osseous tissue origin appeared to be the major source of activity for each group of animals reported.

Entities: Chemical Species

Year: 1983 PMID： 17422242 PMCID： PMC1790296

Source DB: PubMed Journal: Can Vet J ISSN： 0008-5286 Impact factor: 1.008

13 in total

1. HEAT INACTIVATION IN THE STUDY OF HUMAN ALKALINE PHOSPHATASES.

Authors: S POSEN; F C NEALE; J S CLUBB
Journal: Ann Intern Med Date: 1965-06 Impact factor: 25.391

2. Phenylalanine inhibited p-nitrophenyl phosphatase activity in the serum as an indication of intestinal cellular disruption in the horse.

Authors: D J Blackmore; A Palmer
Journal: Res Vet Sci Date: 1977-09 Impact factor: 2.534

3. The differentiation of hepatic and skeletal alkaline phosphatase by thermofractionation.

Authors: C R Ratliff; F F Hall; T W Culp; R E Gevedon; C L Westfall
Journal: Am J Gastroenterol Date: 1972-07 Impact factor: 10.864

4. Organ-identifying properties of alkaline phosphatases from canine tissues.

Authors: L A Nagode; A Koestner; C L Steinmeyer
Journal: Clin Chim Acta Date: 1969-10 Impact factor: 3.786

5. Alkaline phosphatase, leucine aminopeptidase, and alanine aminotransferase activities with obstructive and toxic hepatic disease in cats.

Authors: R M Everett; J R Duncan; K W Prasse
Journal: Am J Vet Res Date: 1977-07 Impact factor: 1.156

9. Routine measurements of liver and bone alkaline phosphatase in human serum. Differential inhibition by L-phenylalanine and carbamide (urea)on the LKB 8600 reaction rate analyzer.

Authors: W Gerhardt; M L Nielsen; O V Nielsen; J S Olsen; B E Statland
Journal: Clin Chim Acta Date: 1974-06-28 Impact factor: 3.786

10. Isoenzymes of equine alkaline phosphatase.

Authors: B G Froscher; L A Nagode
Journal: Am J Vet Res Date: 1979-11 Impact factor: 1.156

2 in total

1. An attempt to determine the tissue origin of equine serum alkaline phosphatase by isoelectric focusing.

Authors: R S Ellison; R M Jacobs
Journal: Can J Vet Res Date: 1990-01 Impact factor: 1.310

2. The isoelectric focusing properties of serum alkaline phosphatase in disease and following prednisolone and phenylbutazone administration in the horse.