Literature DB >> 17420950

Prognostic index for survival in patients after treatment for primary hepatocellular carcinoma.

Mari Kogo1, Ayuko Kano, Yuji Kiuchi, Keiji Mitamura, Keiichiro Yoneyama.   

Abstract

We retrospectively evaluated clinical factors affecting long-term survival after treatment for hepatocellular carcinoma (HCC) to predict the reliability of the prognosis of patients with HCC. We analyzed 157 patients who received treatment for HCC. The prognostic index (PI) was evaluated using the Cox regression model. The overall cumulative survival rates were 79.7% at 1 year, 51.1% at 3 years, and 24.9% at 5 years. The PI was calculated by the following formula, consisting of five factors: PI = 0.637 x number of tumor lesions + 0.103 x tumor diameter + 1.003 x ascites + 0.915 x portal vein tumor thrombosis - 0.006 x cholinesterase + 2.0. It was found that liver function and progression of the tumor are the most important factors for prognosis after treatment for HCC. The PI, based on five factors, will in future be an appropriate index to predict the prognosis of patients with HCC.

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Year:  2007        PMID: 17420950     DOI: 10.1007/s10620-006-9137-x

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN: 0163-2116            Impact factor:   3.199


  25 in total

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4.  Multivariate survival analysis using Cox's regression model.

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Journal:  Hepatology       Date:  1987 Nov-Dec       Impact factor: 17.425

5.  Prognostic factors after hepatic resection for hepatocellular carcinoma with hepatitis C viral infection: univariate and multivariate analysis.

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Review 9.  Transarterial chemoembolization for unresectable hepatocellular carcinoma: meta-analysis of randomized controlled trials.

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