Literature DB >> 17419650

First example of direct RuO4-catalyzed oxidation of isoxazolidines to 3-isoxazolidones.

Anna Piperno1, Ugo Chiacchio, Daniela Iannazzo, Salvatore V Giofrè, Giovanni Romeo, Roberto Romeo.   

Abstract

RuO2/NaIO4 oxidation of 3-unsubstituted isoxazolidines, under ethyl acetate/water biphasic conditions, affords 3-isoxazolidones in good yields. The methodology can be used on both racemic and optically active isoxazolidines.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17419650     DOI： 10.1021/jo070211n

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

1.  The chemoselective reduction of isoxazoline γ-lactams through iminium Aza-Diels-Alder reactions: a short-cut synthesis of aminols as valuable intermediates towards nucleoside derivatives.

Authors:  Misal Giuseppe Memeo; Mariella Mella; Paolo Quadrelli
Journal:  ScientificWorldJournal       Date:  2012-05-02

2.  Chemoselective Oxidation of Isoxazolidines with Ruthenium Tetroxide: A Successful Intertwining of Combined Theoretical and Experimental Data.

Authors:  Laura Legnani; Salvatore V Giofré; Daniela Iannazzo; Consuelo Celesti; Lucia Veltri; Maria Assunta Chiacchio
Journal:  Molecules       Date:  2022-08-24       Impact factor: 4.927

3.  Pyrimidine 2,4-Diones in the Design of New HIV RT Inhibitors.

Authors:  Roberto Romeo; Daniela Iannazzo; Lucia Veltri; Bartolo Gabriele; Beatrice Macchi; Caterina Frezza; Francesca Marino-Merlo; Salvatore V Giofrè
Journal:  Molecules       Date:  2019-05-02       Impact factor: 4.411
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.