Literature DB >> 17419648

A facile approach to the synthesis of chiral 2-substituted benzofurans.

Lidia De Luca1, Giampaolo Giacomelli, Giammario Nieddu.   

Abstract

An effective route to chiral optically active 2-substituted benzofurans directly from carboxylic acids is reported. This procedure, which allows the preparation of alpha-alkyl-2-benzofuranmethanamines from N-protected alpha-amino acids without sensible racemization phenomena, proceeds in good yields under mild conditions with the help of microwave irradiation.

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Year:  2007        PMID: 17419648     DOI: 10.1021/jo070142c

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

1.  A new approach to fused furan ring systems and benzofurans: Intramolecular cyclization reactions of unsaturated acyloxy sulfone derivatives.

Authors:  Yuan Liu; Hollie K Jacobs; Aravamudan S Gopalan
Journal:  Tetrahedron Lett       Date:  2011-06-08       Impact factor: 2.415

  1 in total

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