| Literature DB >> 17419648 |
Lidia De Luca1, Giampaolo Giacomelli, Giammario Nieddu.
Abstract
An effective route to chiral optically active 2-substituted benzofurans directly from carboxylic acids is reported. This procedure, which allows the preparation of alpha-alkyl-2-benzofuranmethanamines from N-protected alpha-amino acids without sensible racemization phenomena, proceeds in good yields under mild conditions with the help of microwave irradiation.Entities:
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Year: 2007 PMID: 17419648 DOI: 10.1021/jo070142c
Source DB: PubMed Journal: J Org Chem ISSN: 0022-3263 Impact factor: 4.354