Literature DB >> 17419010

Serotonergic response to stress: a protective factor against abnormal dopaminergic reactivity in schizophrenia?

Jerome Brunelin1, Thierry D'amato, Jim van Os, Jean Dalery, Marie-Françoise Suaud-Chagny, Mohamed Saoud.   

Abstract

In a double-blind-crossover-study, 10 patients with schizophrenia, 10 of their unaffected siblings and 9 healthy controls randomly received metabolic stressor and placebo. A significant HVA plasma elevation in response to stress was found in siblings whose response was intermediate to that of patients and controls. Only siblings additionally displayed an exaggerated 5HIAA response.

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Year:  2007        PMID: 17419010     DOI: 10.1016/j.eurpsy.2007.01.1219

Source DB:  PubMed          Journal:  Eur Psychiatry        ISSN: 0924-9338            Impact factor:   5.361


  4 in total

1.  Altered integrity of the right arcuate fasciculus as a trait marker of schizophrenia: a sibling study using tractography-based analysis of the whole brain.

Authors:  Chen-Hao Wu; Tzung-Jeng Hwang; Yu-Jen Chen; Yun-Chin Hsu; Yu-Chun Lo; Chih-Min Liu; Hai-Gwo Hwu; Chen-Chung Liu; Ming H Hsieh; Yi Ling Chien; Chung-Ming Chen; Wen-Yih Isaac Tseng
Journal:  Hum Brain Mapp       Date:  2014-11-04       Impact factor: 5.038

Review 2.  Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene-stress interaction.

Authors:  Ruud van Winkel; Nicholas C Stefanis; Inez Myin-Germeys
Journal:  Schizophr Bull       Date:  2008-08-20       Impact factor: 9.306

3.  Autonomic dysfunction in unaffected first-degree relatives of patients suffering from schizophrenia.

Authors:  Karl-Jürgen Bär; Sandy Berger; Maria Metzner; Michael K Boettger; Steffen Schulz; Chaitra T Ramachandraiah; Janneke Terhaar; Andreas Voss; Vikram K Yeragani; Heinrich Sauer
Journal:  Schizophr Bull       Date:  2009-04-14       Impact factor: 9.306

Review 4.  Abnormal striatal dopamine transmission in schizophrenia.

Authors:  Jerome Brunelin; Shirley Fecteau; Marie-Françoise Suaud-Chagny
Journal:  Curr Med Chem       Date:  2013       Impact factor: 4.530

  4 in total

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