| Literature DB >> 17418783 |
Abstract
In mammals, helper T cells orchestrate defense against diverse pathogens. However, these warriors of the immune system can also result in self-inflicted injury culminating in autoimmune and allergic diseases. Recent findings--such as the discovery of the Th17 lineage--have revealed additional complexity in the fates chosen by helper T cells and have begun to reshape our view of how signaling and transcriptional networks generate appropriate and inappropriate immunity.Entities:
Mesh：
Substances：
Year: 2007 PMID： 17418783 DOI： 10.1016/j.cell.2007.03.019
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582