Literature DB >> 17418370

Glycogen synthase kinase-3beta -- actively inhibiting hypertrophy.

Risto Kerkelä1, Kathleen Woulfe, Thomas Force.   

Abstract

A number of signaling pathways are involved in the regulation of cardiac hypertrophy and remodeling. One that serves as an integrator of upstream inputs, and as a transducer to downstream effectors, is the protein kinase, glycogen synthase kinase-3beta. In this work we review the role of this putative "nodal point" in the response of the heart to growth stimuli, both physiologic and pathologic.

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Year:  2007        PMID： 17418370     DOI： 10.1016/j.tcm.2007.01.004

Source DB:  PubMed          Journal:  Trends Cardiovasc Med        ISSN： 1050-1738            Impact factor:   6.677


  20 in total

Review 1.  GSK3beta: role in therapeutic landscape and development of modulators.

Authors:  S Phukan; V S Babu; A Kannoji; R Hariharan; V N Balaji
Journal:  Br J Pharmacol       Date:  2010-03-19       Impact factor: 8.739

Review 2.  The GSK-3 family as therapeutic target for myocardial diseases.

Authors:  Hind Lal; Firdos Ahmad; James Woodgett; Thomas Force
Journal:  Circ Res       Date:  2015-01-02       Impact factor: 17.367

3.  TEAD-1 overexpression in the mouse heart promotes an age-dependent heart dysfunction.

Authors:  Richard W Tsika; Lixin Ma; Izhak Kehat; Christine Schramm; Gretchen Simmer; Brandon Morgan; Deborah M Fine; Laurin M Hanft; Kerry S McDonald; Jeffery D Molkentin; Maike Krenz; Steve Yang; Juan Ji
Journal:  J Biol Chem       Date:  2010-03-01       Impact factor: 5.157

4.  Soluble 3',6-substituted indirubins with enhanced selectivity toward glycogen synthase kinase -3 alter circadian period.

Authors:  Konstantina Vougogiannopoulou; Yoan Ferandin; Karima Bettayeb; Vassilios Myrianthopoulos; Olivier Lozach; Yunzhen Fan; Carl Hirschie Johnson; Prokopios Magiatis; Alexios-Leandros Skaltsounis; Emmanuel Mikros; Laurent Meijer
Journal:  J Med Chem       Date:  2008-09-25       Impact factor: 7.446

Review 5.  Glycogen synthase kinase 3 (GSK3) in the heart: a point of integration in hypertrophic signalling and a therapeutic target? A critical analysis.

Authors:  P H Sugden; S J Fuller; S C Weiss; A Clerk
Journal:  Br J Pharmacol       Date:  2008-01-21       Impact factor: 8.739

Review 6.  Autophagy in load-induced heart disease.

Authors:  Beverly A Rothermel; Joseph A Hill
Journal:  Circ Res       Date:  2008-12-05       Impact factor: 17.367

7.  Glycogen synthase kinase 3beta is a novel regulator of high glucose- and high insulin-induced extracellular matrix protein synthesis in renal proximal tubular epithelial cells.

Authors:  Meenalakshmi M Mariappan; Megan Shetty; Kavithalakshmi Sataranatarajan; Goutam Ghosh Choudhury; Balakuntalam S Kasinath
Journal:  J Biol Chem       Date:  2008-08-12       Impact factor: 5.157

8.  Oleanolic acid alleviated pressure overload-induced cardiac remodeling.

Authors:  Hai-Han Liao; Nan Zhang; Hong Feng; Ning Zhang; Zhen-Guo Ma; Zheng Yang; Yuan Yuan; Zhou-Yan Bian; Qi-Zhu Tang
Journal:  Mol Cell Biochem       Date:  2015-07-28       Impact factor: 3.396

9.  GSK3beta is a negative regulator of platelet function and thrombosis.

Authors:  Dongjun Li; Shelley August; Donna S Woulfe
Journal:  Blood       Date:  2008-01-24       Impact factor: 22.113

Review 10.  WNT Signaling in Cardiac and Vascular Disease.

Authors:  Sébastien Foulquier; Evangelos P Daskalopoulos; Gentian Lluri; Kevin C M Hermans; Arjun Deb; W Matthijs Blankesteijn
Journal:  Pharmacol Rev       Date:  2018-01       Impact factor: 25.468
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