Literature DB >> 1741786

Anti-neoplastic glucuronide prodrug treatment of human tumor cells targeted with a monoclonal antibody-enzyme conjugate.

S R Roffler1, S M Wang, J W Chern, M Y Yeh, E Tung.   

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Year:  1991        PMID: 1741786     DOI: 10.1016/0006-2952(91)90612-9

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN: 0006-2952            Impact factor:   5.858


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  7 in total

1.  Analysis of antibody-enzyme conjugate clearance by investigation of prodrug and active drug in an ADEPT clinical study.

Authors:  C J Springer; G K Poon; S K Sharma; K D Bagshawe
Journal:  Cell Biophys       Date:  1994

Review 2.  Antibody-directed enzyme prodrug therapy.

Authors:  K D Bagshawe
Journal:  Clin Pharmacokinet       Date:  1994-11       Impact factor: 6.447

3.  Amide-based prodrugs of spermidine-bridged dinuclear platinum. Synthesis, DNA binding, and biological activity.

Authors:  Alexander Hegmans; Jana Kasparkova; Oldrich Vrana; Lloyd R Kelland; Viktor Brabec; Nicholas P Farrell
Journal:  J Med Chem       Date:  2008-03-14       Impact factor: 7.446

4.  Bystander killing of tumour cells by antibody-targeted enzymatic activation of a glucuronide prodrug.

Authors:  T L Cheng; S L Wei; B M Chen; J W Chern; M F Wu; P W Liu; S R Roffler
Journal:  Br J Cancer       Date:  1999-03       Impact factor: 7.640

5.  ATIQCTPC: a nanomedicine capable of targeting tumor and blocking thrombosis in vivo.

Authors:  Xinyi Xu; Yuji Wang; Jianhui Wu; Xi Hu; Haimei Zhu; Xiaoyi Zhang; Yaonan Wang; Lin Gui; Ming Zhao; Shiqi Peng
Journal:  Int J Nanomedicine       Date:  2017-06-13

6.  A monoclonal antibody-beta-glucuronidase conjugate as activator of the prodrug epirubicin-glucuronide for specific treatment of cancer.

Authors:  H J Haisma; E Boven; M van Muijen; J de Jong; W J van der Vijgh; H M Pinedo
Journal:  Br J Cancer       Date:  1992-09       Impact factor: 7.640

Review 7.  Targeting enzymes for cancer therapy: old enzymes in new roles.

Authors:  M P Deonarain; A A Epenetos
Journal:  Br J Cancer       Date:  1994-11       Impact factor: 7.640

  7 in total

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