Literature DB >> 17417855

Kedarcidin chromophore: synthesis of its proposed structure and evidence for a stereochemical revision.

Feng Ren1, Philip C Hogan, Alan J Anderson, Andrew G Myers.   

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Year:  2007        PMID: 17417855      PMCID: PMC3174495          DOI: 10.1021/ja071205b

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


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  5 in total

1.  Synthesis of the Kedarcidin Core Structure by a Transannular Cyclization Pathway Financial support from the National Institutes of Health is gratefully acknowledged.

Authors: 
Journal:  Angew Chem Int Ed Engl       Date:  2000-08-04       Impact factor: 15.336

2.  Enantioselective synthesis of kedarcidin chromophore aglycon in differentially protected form.

Authors:  Andrew G Myers; Philip C Hogan; Alexander R Hurd; Steven D Goldberg
Journal:  Angew Chem Int Ed Engl       Date:  2002-03-15       Impact factor: 15.336

3.  A Direct and Efficient alpha-Selective Glycosylation Protocol for the Kedarcidin Sugar, L-Mycarose: AgPF(6) as a Remarkable Activator of 2-Deoxythioglycosides This work was supported by CREST, and fellowships (to M.J.L. and F.Y.) from the Japanese Society for the Promotion of Science are gratefully acknowledged.

Authors:  Martin J. Lear; Fumihiko Yoshimura; Masahiro Hirama
Journal:  Angew Chem Int Ed Engl       Date:  2001-03-02       Impact factor: 15.336

4.  Evidence for facile atropisomerism and simple (non-nucleophilic) biradical-forming cycloaromatization within kedarcidin chromophore aglycon.

Authors:  Andrew G Myers; Alexander R Hurd; Philip C Hogan
Journal:  J Am Chem Soc       Date:  2002-05-01       Impact factor: 15.419

5.  Highly selective synthesis of (E)-3-methyl-1-trialkylsilyl-3-en-1-ynes via trans-selective alkynylation catalyzed by Cl2Pd(DPEphos) and stereospecific methylation with methylzincs catalyzed by Pd(tBu3P)2.

Authors:  Ji-Cheng Shi; Xingzhong Zeng; Ei-Ichi Negishi
Journal:  Org Lett       Date:  2003-05-29       Impact factor: 6.005

  5 in total
  12 in total

1.  Genome neighborhood network reveals insights into enediyne biosynthesis and facilitates prediction and prioritization for discovery.

Authors:  Jeffrey D Rudolf; Xiaohui Yan; Ben Shen
Journal:  J Ind Microbiol Biotechnol       Date:  2015-08-29       Impact factor: 3.346

Review 2.  Methods for 2-Deoxyglycoside Synthesis.

Authors:  Clay S Bennett; M Carmen Galan
Journal:  Chem Rev       Date:  2018-06-28       Impact factor: 60.622

Review 3.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

4.  Synthesis of the Non-Reducing Hexasaccharide Fragment of Saccharomicin B.

Authors:  Manas Jana; Clay S Bennett
Journal:  Org Lett       Date:  2018-11-14       Impact factor: 6.005

5.  Cloning and sequencing of the kedarcidin biosynthetic gene cluster from Streptoalloteichus sp. ATCC 53650 revealing new insights into biosynthesis of the enediyne family of antitumor antibiotics.

Authors:  Jeremy R Lohman; Sheng-Xiong Huang; Geoffrey P Horsman; Paul E Dilfer; Tingting Huang; Yihua Chen; Evelyn Wendt-Pienkowski; Ben Shen
Journal:  Mol Biosyst       Date:  2013-01-29

6.  A new member of the 4-methylideneimidazole-5-one-containing aminomutase family from the enediyne kedarcidin biosynthetic pathway.

Authors:  Sheng-Xiong Huang; Jeremy R Lohman; Tingting Huang; Ben Shen
Journal:  Proc Natl Acad Sci U S A       Date:  2013-04-30       Impact factor: 11.205

7.  Inspirations, discoveries, and future perspectives in total synthesis.

Authors:  K C Nicolaou
Journal:  J Org Chem       Date:  2009-02-06       Impact factor: 4.354

Review 8.  Enediynes: Exploration of microbial genomics to discover new anticancer drug leads.

Authors:  Ben Shen; Xiaohui Yan; Tingting Huang; Huiming Ge; Dong Yang; Qihui Teng; Jeffrey D Rudolf; Jeremy R Lohman
Journal:  Bioorg Med Chem Lett       Date:  2014-11-14       Impact factor: 2.823

9.  Component-based syntheses of trioxacarcin A, DC-45-A1 and structural analogues.

Authors:  Thomas Magauer; Daniel J Smaltz; Andrew G Myers
Journal:  Nat Chem       Date:  2013-09-08       Impact factor: 24.427

10.  A convergent, umpoled synthesis of 2-(1-amidoalkyl)pyridines.

Authors:  Tarn C Johnson; Stephen P Marsden
Journal:  Beilstein J Org Chem       Date:  2016-01-04       Impact factor: 2.883

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