BACKGROUND: Juvenile idiopathic arthritis (JIA) is the most common cause of chronic arthritis in children, with frequent involvement of the metacarpophalangeal joints (MCPJ). OBJECTIVE: To compare US findings with those of radiography and clinical examination. MATERIALS AND METHODS: All MCPJs in 20 children with JIA (17 females, median age 9.7 years, range 3.6 to 16.8 years) were evaluated clinically and imaged with gray-scale and color Doppler US, and 90 MCPJs were also imaged radiographically. Each MCPJ was graded on physical examination from 0 (normal) to 4 (severe) by the patient's rheumatologist. RESULTS: US demonstrated abnormalities in 64 of 200 MCPJs (32.0%), including pannus vascularity and/or tenosynovitis in 55 joints (27.5%) (pannus vascularity in 43, tenosynovitis in 40) and bone destruction in 25 joints (12.5%). Overall, US abnormalities and physical examination scores were significantly associated (P < 0.001). However, interobserver agreement between US and clinical evaluation was poor (kappa 0.1) and between US and radiography was only fair (kappa 0.4). CONCLUSION: US of the MCPJ in children with JIA can demonstrate cartilage thinning, bone erosions, and pannus vascularity. Abnormal US findings are significantly correlated with severity of disease as evaluated clinically.
BACKGROUND:Juvenile idiopathic arthritis (JIA) is the most common cause of chronic arthritis in children, with frequent involvement of the metacarpophalangeal joints (MCPJ). OBJECTIVE: To compare US findings with those of radiography and clinical examination. MATERIALS AND METHODS: All MCPJs in 20 children with JIA (17 females, median age 9.7 years, range 3.6 to 16.8 years) were evaluated clinically and imaged with gray-scale and color Doppler US, and 90 MCPJs were also imaged radiographically. Each MCPJ was graded on physical examination from 0 (normal) to 4 (severe) by the patient's rheumatologist. RESULTS: US demonstrated abnormalities in 64 of 200 MCPJs (32.0%), including pannus vascularity and/or tenosynovitis in 55 joints (27.5%) (pannus vascularity in 43, tenosynovitis in 40) and bone destruction in 25 joints (12.5%). Overall, US abnormalities and physical examination scores were significantly associated (P < 0.001). However, interobserver agreement between US and clinical evaluation was poor (kappa 0.1) and between US and radiography was only fair (kappa 0.4). CONCLUSION: US of the MCPJ in children with JIA can demonstrate cartilage thinning, bone erosions, and pannus vascularity. Abnormal US findings are significantly correlated with severity of disease as evaluated clinically.
Authors: Markus Walther; Harry Harms; Veit Krenn; Stephan Radke; Stephan Kirschner; Frank Gohlke Journal: Radiology Date: 2002-10 Impact factor: 11.105
Authors: M Backhaus; T Kamradt; D Sandrock; D Loreck; J Fritz; K J Wolf; H Raber; B Hamm; G R Burmester; M Bollow Journal: Arthritis Rheum Date: 1999-06
Authors: V M Gylys-Morin; T B Graham; J S Blebea; B J Dardzinski; T Laor; N D Johnson; A E Oestreich; M H Passo Journal: Radiology Date: 2001-09 Impact factor: 11.105
Authors: R J Wakefield; W W Gibbon; P G Conaghan; P O'Connor; D McGonagle; C Pease; M J Green; D J Veale; J D Isaacs; P Emery Journal: Arthritis Rheum Date: 2000-12
Authors: Karen Lambot; Peter Boavida; Maria Beatrice Damasio; Laura Tanturri de Horatio; Marie Desgranges; Clara Malattia; Domenico Barbuti; Claudia Bracaglia; Lil-Sofie Ording Müller; Caroline Elie; Brigitte Bader-Meunier; Pierre Quartier; Karen Rosendahl; Francis Brunelle Journal: Pediatr Radiol Date: 2013-02-05
Authors: Gordon J Hendry; Deborah E Turner; John McColl; Paula K Lorgelly; Roger D Sturrock; Gordon F Watt; Michael Browne; Janet Gardner-Medwin; Lorraine Friel; Jim Woodburn Journal: J Foot Ankle Res Date: 2009-06-30 Impact factor: 2.303
Authors: Derk Frederik Matthaus Avenarius; Charlotte Nusman; Clara Malattia; Laura Tanturri de Horatio; Karen Rosendahl; Mario Maas; Lil-Sofie Ording Müller Journal: Pediatr Radiol Date: 2018-05-08