Literature DB >> 17415464

Relationship between natural concentration of heavy water isotopologs and rate of H2O2 generation by mitochondria.

I A Pomytkin1, O E Kolesova.   

Abstract

Relationship between natural concentration of heavy water isotope homologs in natural water and the kinetics of H(2)O(2) generation by isolated rat liver mitochondria in the presence of succinic acid as the substrate was studied. Natural concentrations of heavy water isotopologs significantly inhibited the studied reaction. The decrease in heavy isotopolog content in natural water leads to disinhibition and significant acceleration of the studied reaction.

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Year:  2006        PMID： 17415464     DOI： 10.1007/s10517-006-0420-9

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  10 in total

Review 1.  Can heavy isotopes increase lifespan? Studies of relative abundance in various organisms reveal chemical perspectives on aging.

Authors:  Xiyan Li; Michael P Snyder
Journal:  Bioessays       Date:  2016-08-24       Impact factor: 4.345

2.  In Vitro Study of Deuterium Effect on Biological Properties of Human Cultured Adipose-Derived Stem Cells.

Authors:  Alona Zlatska; Inna Gordiienko; Roman Vasyliev; Dmitriy Zubov; Olga Gubar; Anzhela Rodnichenko; Anton Syroeshkin; Igor Zlatskiy
Journal:  ScientificWorldJournal       Date:  2018-11-04

Review 3.  Deuterium-Depleted Water Influence on the Isotope 2H/1H Regulation in Body and Individual Adaptation.

Authors:  Alexander Basov; Liliia Fedulova; Mikhail Baryshev; Stepan Dzhimak
Journal:  Nutrients       Date:  2019-08-15       Impact factor: 5.717

4.  Anticancer Effect of Deuterium Depleted Water - Redox Disbalance Leads to Oxidative Stress.

Authors:  Xuepei Zhang; Massimiliano Gaetani; Alexey Chernobrovkin; Roman A Zubarev
Journal:  Mol Cell Proteomics       Date:  2019-09-13       Impact factor: 5.911

Review 5.  Possible Mechanisms of Biological Effects Observed in Living Systems during 2H/1H Isotope Fractionation and Deuterium Interactions with Other Biogenic Isotopes.

Authors:  Alexander Basov; Liliya Fedulova; Ekaterina Vasilevskaya; Stepan Dzhimak
Journal:  Molecules       Date:  2019-11-13       Impact factor: 4.411

6.  Inequality in the Frequency of the Open States Occurrence Depends on Single 2H/1H Replacement in DNA.

Authors:  Alexander Basov; Mikhail Drobotenko; Alexandr Svidlov; Eugeny Gerasimenko; Vadim Malyshko; Anna Elkina; Mikhail Baryshev; Stepan Dzhimak
Journal:  Molecules       Date:  2020-08-18       Impact factor: 4.411

7.  Yeast longevity promoted by reversing aging-associated decline in heavy isotope content.

Authors:  Xiyan Li; Michael P Snyder
Journal:  NPJ Aging Mech Dis       Date:  2016-02-18

8.  Comparative Analysis of the Different Dyes' Potential to Assess Human Normal and Cancer Cell Viability In Vitro under Different D/H Ratios in a Culture Medium.

Authors:  I A Zlatskiy; A V Zlatska; N V Antipova; S A Dolenko; I M Gordiienko; O S Gubar; R G Vasyliev; D A Zubov; S N Novikova; A V Syroeshkin
Journal:  ScientificWorldJournal       Date:  2020-02-25

9.  Deuterium-Depleted Water as Adjuvant Therapeutic Agent for Treatment of Diet-Induced Obesity in Rats.

Authors:  Tetiana Halenova; Igor Zlatskiy; Anton Syroeshkin; Tatiana Maximova; Tatiana Pleteneva
Journal:  Molecules       Date:  2019-12-19       Impact factor: 4.411

10.  Blocking the Increase of Intracellular Deuterium Concentration Prevents the Expression of Cancer-Related Genes, Tumor Development, and Tumor Recurrence in Cancer Patients.

Authors:  Beáta Zs Kovács; László G Puskás; Lajos I Nagy; András Papp; Zoltán Gyöngyi; István Fórizs; György Czuppon; Ildikó Somlyai; Gábor Somlyai
Journal:  Cancer Control       Date:  2022 Jan-Dec       Impact factor: 3.302
  10 in total

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