Literature DB >> 17415133

Congenital cholesteatoma: risk factors for residual disease and retraction pockets--a report on 117 cases.

Diane S Lazard1, Gilles Roger, Françoise Denoyelle, Pierre Chauvin, Erea-Noel Garabédian.   

Abstract

OBJECTIVES: To define predictors of residuals and retraction pockets (RP) in children operated on for congenital cholesteatoma (CC). DESIGN AND
SETTING: Retrospective review (1996-2005), academic center. PATIENTS: One hundred seventeen patients treated for CC corresponding to modified Derlacki's criteria were included (median age, 6.5 yr). No case of RP at time of diagnosis, with a mean follow-up of 2.5 years after last surgery. MAIN OUTCOME MEASURES: Clinical and surgical data influencing outcome. Multivariate analysis.
RESULTS: Two groups were defined after CC removal: group I (12 cases), no second look required and no case of subsequent re-intervention; group II (105 cases), planned second look always performed (mean delay, 12.1 mo), no difference of sex ratio (M/F = 2). Group I patients were younger than in group II (3.3 vs. 5.9 yr, P < .001). All of them had a normal contralateral eardrum and a disclosure of CC by routine examination (vs. 19% in group II, P < .001). In group I, the mass occupied one or two anterior quadrants (41.6% and 58.4%, respectively) versus more than two quadrants in 46.6% in group II. Residuals and RP rates were 41% and 15%, respectively (only in group II). Predictors for residuals were atticotomy (odds ratio [OR] 2.9, 95% confidence interval [CI] 1.3-6.7) and destruction of stapes (OR 4.3, 95% CI 1.7-10.5). Predictors for RP were eustachian tube extension (OR 6.8, 95% CI 1.7-26.8) and nonreconstructed atticotomy (OR 5.9, 95% CI 1.1-30.9).
CONCLUSIONS: Young children with small CC had no recurrences. Residuals were more frequent in case of atticotomy and stapes destruction. RP occurred especially in cases of eustachian tube extension and if cartilage tympanoplasty was not performed. Tympanic and canal wall reinforcement should be considered in extensive CC.

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Year:  2007        PMID: 17415133     DOI: 10.1097/mlg.0b013e318030ac8c

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  5 in total

1.  Pediatric middle ear cholesteatoma: the comparative study of congenital cholesteatoma and acquired cholesteatoma.

Authors:  Yuka Morita; Yutaka Yamamoto; Shinsuke Oshima; Kuniyuki Takahashi; Sugata Takahashi
Journal:  Eur Arch Otorhinolaryngol       Date:  2015-06-05       Impact factor: 2.503

2.  Clinical Characteristics and Treatment Outcomes of Congenital Cholesteatoma.

Authors:  In Sik Song; Won Gue Han; Kang Hyeon Lim; Kuk Jin Nam; Myung Hoon Yoo; Yoon Chan Rah; June Choi
Journal:  J Int Adv Otol       Date:  2019-12       Impact factor: 1.017

3.  [Current aspects of paediatric cholesteatomas].

Authors:  J P Thomas; S Volkenstein; A Minovi; S Dazert
Journal:  HNO       Date:  2013-05       Impact factor: 1.284

4.  Middle ear congenital cholesteatoma: systematic review, meta-analysis and insights on its pathogenesis.

Authors:  Nelson Gilberto; Sara Custódio; Tiago Colaço; Ricardo Santos; Pedro Sousa; Pedro Escada
Journal:  Eur Arch Otorhinolaryngol       Date:  2020-01-18       Impact factor: 2.503

5.  Identification of risk factors for residual cholesteatoma in children and adults: a retrospective study on 110 cases of revision surgery.

Authors:  Veronika Volgger; Göran Lindeskog; Eike Krause; Florian Schrötzlmair
Journal:  Braz J Otorhinolaryngol       Date:  2018-12-31
  5 in total

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