Literature DB >> 17415043

Elevated plasma levels of high mobility group box protein 1 in patients with HIV-1 infection.

Piotr Nowak1, Babilonia Barqasho, Anders Sönnerborg.   

Abstract

High mobility group box protein 1 (HMGB1) is a potent proinflammatory mediator. It has a dichotomic effect on HIV-1 replication in vitro but its role in vivo is unknown. Here we report the novel finding that plasma HMGB1 levels are elevated in HIV-1-infected patients, with the highest concentrations in patients with clinical complications. HMGB1 is likely to contribute to immunoactivation in HIV-1 infection in vivo.

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Year:  2007        PMID: 17415043     DOI: 10.1097/QAD.0b013e3280b079b6

Source DB:  PubMed          Journal:  AIDS        ISSN: 0269-9370            Impact factor:   4.177


  13 in total

1.  Escape of HIV-1-infected dendritic cells from TRAIL-mediated NK cell cytotoxicity during NK-DC cross-talk--a pivotal role of HMGB1.

Authors:  Marie-Thérèse Melki; Héla Saïdi; Alexandre Dufour; Jean-Christophe Olivo-Marin; Marie-Lise Gougeon
Journal:  PLoS Pathog       Date:  2010-04-15       Impact factor: 6.823

Review 2.  HMGB1 in health and disease.

Authors:  Rui Kang; Ruochan Chen; Qiuhong Zhang; Wen Hou; Sha Wu; Lizhi Cao; Jin Huang; Yan Yu; Xue-Gong Fan; Zhengwen Yan; Xiaofang Sun; Haichao Wang; Qingde Wang; Allan Tsung; Timothy R Billiar; Herbert J Zeh; Michael T Lotze; Daolin Tang
Journal:  Mol Aspects Med       Date:  2014-07-08

3.  High mobility group box 1 protein as an auxiliary biomarker for dengue diagnosis.

Authors:  Diego Allonso; Susana Vázquez; Maria G Guzmán; Ronaldo Mohana-Borges
Journal:  Am J Trop Med Hyg       Date:  2012-12-26       Impact factor: 2.345

Review 4.  Learning from the messengers: innate sensing of viruses and cytokine regulation of immunity - clues for treatments and vaccines.

Authors:  Jesper Melchjorsen
Journal:  Viruses       Date:  2013-01-31       Impact factor: 5.048

Review 5.  HMGB1, an alarmin promoting HIV dissemination and latency in dendritic cells.

Authors:  M-L Gougeon; M-T Melki; H Saïdi
Journal:  Cell Death Differ       Date:  2011-10-28       Impact factor: 15.828

6.  Impact of HMGB1/TLR Ligand Complexes on HIV-1 Replication: Possible Role for Flagellin during HIV-1 Infection.

Authors:  Piotr Nowak; Samir Abdurahman; Annica Lindkvist; Marius Troseid; Anders Sönnerborg
Journal:  Int J Microbiol       Date:  2012-06-06

7.  HMGB1 Is Involved in IFN-α Production and TRAIL Expression by HIV-1-Exposed Plasmacytoid Dendritic Cells: Impact of the Crosstalk with NK Cells.

Authors:  Héla Saïdi; Marlène Bras; Pauline Formaglio; Marie-Thérèse Melki; Bruno Charbit; Jean-Philippe Herbeuval; Marie-Lise Gougeon
Journal:  PLoS Pathog       Date:  2016-02-12       Impact factor: 6.823

8.  The Initial Months of Antiretroviral Therapy and Its Influence on AGEs, HMGB1, and sRAGE Levels in Asymptomatic HIV-Infected Individuals.

Authors:  Karen Ingrid Tasca; Juliana Trindade Caleffi; Camila Renata Correa; Mariana Gatto; Caio Cavassan de Camargo; Monica Bannwart Mendes; Marjorie de Assis Golim; Mara Biasin; Lenice do Rosário de Souza
Journal:  Mediators Inflamm       Date:  2016-11-30       Impact factor: 4.711

9.  Bench-to-bedside review: High-mobility group box 1 and critical illness.

Authors:  Mitchell P Fink
Journal:  Crit Care       Date:  2007       Impact factor: 9.097

10.  HMGB1-dependent triggering of HIV-1 replication and persistence in dendritic cells as a consequence of NK-DC cross-talk.

Authors:  Héla Saïdi; Marie-Thérèse Melki; Marie-Lise Gougeon
Journal:  PLoS One       Date:  2008-10-31       Impact factor: 3.240

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