OBJECTIVES: To evaluate the relationship between douching and bacterial vaginosis (BV) among women with and without prior abnormal vaginal flora. STUDY DESIGNS: 1193 women had vaginal swabs obtained for Gram stain for BV, culture for vaginal microflora, and DNA amplification for Neisseria gonorrhoeae and Chlamydia trachomatis at baseline and 6, 12, 24, and 36 months. Self-reported douching was queried every 6 months. RESULTS: In cross-sectional analyses, douching at least once per month was associated with BV among women who had BV at the immediately preceding visit but not among women with normal or intermediate flora. In prospective analyses, douching increased the risk of acquisition for BV among women with intermediate flora (adj. HR 1.5, 95% CI 1.1-2.4) but not among women with normal flora. CONCLUSIONS: Douching appeared to be associated with BV among women with already imbalanced flora but not among women with normal flora.
OBJECTIVES: To evaluate the relationship between douching and bacterial vaginosis (BV) among women with and without prior abnormal vaginal flora. STUDY DESIGNS: 1193 women had vaginal swabs obtained for Gram stain for BV, culture for vaginal microflora, and DNA amplification for Neisseria gonorrhoeae and Chlamydia trachomatis at baseline and 6, 12, 24, and 36 months. Self-reported douching was queried every 6 months. RESULTS: In cross-sectional analyses, douching at least once per month was associated with BV among women who had BV at the immediately preceding visit but not among women with normal or intermediate flora. In prospective analyses, douching increased the risk of acquisition for BV among women with intermediate flora (adj. HR 1.5, 95% CI 1.1-2.4) but not among women with normal flora. CONCLUSIONS: Douching appeared to be associated with BV among women with already imbalanced flora but not among women with normal flora.
Authors: Hayley Mark; Susan G Sherman; Joy Nanda; Tracey Chambers-Thomas; Mathilda Barnes; Anne Rompalo Journal: Public Health Nurs Date: 2010 Sep-Oct Impact factor: 1.462
Authors: Rebecca M Brotman; Khalil G Ghanem; Mark A Klebanoff; Taha E Taha; Daniel O Scharfstein; Jonathan M Zenilman Journal: Am J Obstet Gynecol Date: 2008-03-04 Impact factor: 8.661
Authors: P Madhivanan; K Krupp; V Chandrasekaran; C Karat; A Arun; C R Cohen; A L Reingold; J D Klausner Journal: Indian J Med Microbiol Date: 2008 Apr-Jun Impact factor: 0.985
Authors: R Scott McClelland; Barbra A Richardson; Susan M Graham; Linnet N Masese; Ruth Gitau; Ludo Lavreys; Kishorchandra Mandaliya; Walter Jaoko; Jared M Baeten; Jeckoniah O Ndinya-Achola Journal: Sex Transm Dis Date: 2008-06 Impact factor: 2.830
Authors: Mark A Klebanoff; Tonja R Nansel; Rebecca M Brotman; Jun Zhang; Kai-Fun Yu; Jane R Schwebke; William W Andrews Journal: Sex Transm Dis Date: 2010-02 Impact factor: 2.830
Authors: Rebecca M Brotman; Mark A Klebanoff; Tonja R Nansel; William W Andrews; Jane R Schwebke; Jun Zhang; Kai F Yu; Jonathan M Zenilman; Daniel O Scharfstein Journal: Am J Epidemiol Date: 2008-05-23 Impact factor: 4.897