Literature DB >> 17413413

The role of botulinum toxin in the management of head and neck cancer patients.

Rainer Laskawi1, Maik Ellies.   

Abstract

PURPOSE OF REVIEW: In this review article different relevant applications of botulinum toxin type A are demonstrated in patients with head and neck cancer. RECENT
FINDINGS: Patients with head and neck cancers of different etiologies often suffer from disorders concerning their musculature (for example, synkinesis in mimic muscles) or gland secretion in the head and neck region. This leads to many problems and reduces their quality of life. The application of botulinum toxin type A can improve movement disorders like synkinesis following reconstructive surgery in patients with cancers of the parotid gland, spasms of the pharyngo-esophageal musculature following laryngectomies and disorders of the autonomous nerve system like hypersalivation, hyperlacrimation and pathological sweating.
SUMMARY: The application of botulinum toxin type A is a helpful and minimally invasive treatment option in different functional disorders improving the quality of life in patients with head and neck cancers of different etiologies. Side effects are rare.

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Year:  2007        PMID: 17413413     DOI: 10.1097/MOO.0b013e328014731c

Source DB:  PubMed          Journal:  Curr Opin Otolaryngol Head Neck Surg        ISSN: 1068-9508            Impact factor:   2.064


  4 in total

Review 1.  Botulinum neurotoxin: evolution from poison, to research tool--onto medicinal therapeutic and future pharmaceutical panacea.

Authors:  Richard M Kostrzewa; Juan Segura-Aguilar
Journal:  Neurotox Res       Date:  2007-12       Impact factor: 3.911

2.  Intratympanic application of botulinum toxin: experiments in guinea pigs for excluding ototoxic effects.

Authors:  Thorsten Zehlicke; Christoph Punke; Dirk Dressler; Hans Wilhelm Pau
Journal:  Eur Arch Otorhinolaryngol       Date:  2007-09-01       Impact factor: 2.503

3.  Botulinum toxin injection and phenol nerve block for reduction of end-of-life pain.

Authors:  Jack Fu; An Ngo; Ki Shin; Eduardo Bruera
Journal:  J Palliat Med       Date:  2013-11-16       Impact factor: 2.947

Review 4.  Applications of botulinum toxin in dentistry: A comprehensive review.

Authors:  Sanjeev Srivastava; Smriti Kharbanda; U S Pal; Vinit Shah
Journal:  Natl J Maxillofac Surg       Date:  2015 Jul-Dec
  4 in total

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