BACKGROUND: The evaluation of quality of life and self-perceived health represents an assessment of the impact of treatment on patient functioning and well-being. OBJECTIVE: Our aim was to explore the impact of methadone maintenance treatment on quality of life and self-perceived health of opioid-dependent persons in Lithuania. METHODS: A total of 102 opioid-dependent patients were recruited in the study. A prospective follow-up study design was used. To assess quality of life, the WHOQOL-BREF 26-item version was used. The impact of methadone maintenance treatment on self-perceived health was assessed by Opiate Treatment Index (OTI). RESULTS: Following 6 months of methadone maintenance treatment, significant improvements in physical (P=0.004), psychological (P=0.004), and environmental (P=0.048) components of quality of life were observed; no statistically significant improvements were found in social component of quality of life. Study participants reported lower rates of medical morbidity associated with injection (P<0.001), cardiorespiratory (P=0.034), musculoskeletal (P<0.001), neurological (P=0.013), gastrointestinal (P<0.001), and general health (P<0.001). CONCLUSIONS: Methadone maintenance treatment substantially reduces morbidity associated with opioid dependence and improves the quality of life of patients.
BACKGROUND: The evaluation of quality of life and self-perceived health represents an assessment of the impact of treatment on patient functioning and well-being. OBJECTIVE: Our aim was to explore the impact of methadone maintenance treatment on quality of life and self-perceived health of opioid-dependent persons in Lithuania. METHODS: A total of 102 opioid-dependent patients were recruited in the study. A prospective follow-up study design was used. To assess quality of life, the WHOQOL-BREF 26-item version was used. The impact of methadone maintenance treatment on self-perceived health was assessed by Opiate Treatment Index (OTI). RESULTS: Following 6 months of methadone maintenance treatment, significant improvements in physical (P=0.004), psychological (P=0.004), and environmental (P=0.048) components of quality of life were observed; no statistically significant improvements were found in social component of quality of life. Study participants reported lower rates of medical morbidity associated with injection (P<0.001), cardiorespiratory (P=0.034), musculoskeletal (P<0.001), neurological (P=0.013), gastrointestinal (P<0.001), and general health (P<0.001). CONCLUSIONS:Methadone maintenance treatment substantially reduces morbidity associated with opioid dependence and improves the quality of life of patients.
Authors: Lidia Z Meshesha; Judith I Tsui; Jane M Liebschutz; Denise Crooks; Bradley J Anderson; Debra S Herman; Michael D Stein Journal: Addict Behav Date: 2013-08-14 Impact factor: 3.913
Authors: Jeganathan Premila Devi; Ab Rahman Azriani; Wan Mohd Zahiruddin; Mohd Noor Mohd Ariff; Abdullah Noor Hashimah Journal: Malays J Med Sci Date: 2012-10
Authors: Shannon Gwin Mitchell; Jan Gryczynski; Robert P Schwartz; C Patrick Myers; Kevin E O'Grady; Yngvild K Olsen; Jerome H Jaffe Journal: J Psychoactive Drugs Date: 2015 Apr-Jun
Authors: Jessica De Maeyer; Wouter Vanderplasschen; Jan Lammertyn; Chijs van Nieuwenhuizen; Bernard Sabbe; Eric Broekaert Journal: Qual Life Res Date: 2010-08-26 Impact factor: 4.147