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Literature DB >> 17412322

Focus on molecules: lacritin.

Peisong Ma¹, Ningning Wang, Robert L McKown, Ronald W Raab, Gordon W Laurie.

Abstract

Mesh：

Substances：

Year: 2007 PMID： 17412322 PMCID： PMC2277456 DOI： 10.1016/j.exer.2007.01.025

Source DB: PubMed Journal: Exp Eye Res ISSN： 0014-4835 Impact factor: 3.467

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4 in total

1. cDNA and genomic cloning of lacritin, a novel secretion enhancing factor from the human lacrimal gland.

Authors: S Sanghi; R Kumar; A Lumsden; D Dickinson; V Klepeis; V Trinkaus-Randall; H F Frierson; G W Laurie
Journal: J Mol Biol Date: 2001-06-29 Impact factor: 5.469

2. Proteomic analysis of human meibomian gland secretions.

Authors: P S Tsai; J E Evans; K M Green; R M Sullivan; D A Schaumberg; S M Richards; M R Dana; D A Sullivan
Journal: Br J Ophthalmol Date: 2006-03 Impact factor: 4.638

3. Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin.

Authors: Peisong Ma; Shannon L Beck; Ronald W Raab; Robert L McKown; George L Coffman; Atsushi Utani; William J Chirico; Alan C Rapraeger; Gordon W Laurie
Journal: J Cell Biol Date: 2006-09-18 Impact factor: 10.539

4. Restricted epithelial proliferation by lacritin via PKCalpha-dependent NFAT and mTOR pathways.

Authors: Jiahu Wang; Ningning Wang; Jinling Xie; Staci C Walton; Robert L McKown; Ronald W Raab; Peisong Ma; Shannon L Beck; George L Coffman; Isa M Hussaini; Gordon W Laurie
Journal: J Cell Biol Date: 2006-08-21 Impact factor: 10.539

4 in total

8 in total

1. Dry eye and designer ophthalmics.

Authors: Gordon W Laurie; Leslie A Olsakovsky; Brian P Conway; Robert L McKown; Kazuko Kitagawa; Jason J Nichols
Journal: Optom Vis Sci Date: 2008-08 Impact factor: 1.973

Review 2. Antimicrobial compounds in tears.

Authors: Alison M McDermott
Journal: Exp Eye Res Date: 2013-07-20 Impact factor: 3.467

3. In vitro studies on the antimicrobial peptide human beta-defensin 9 (HBD9): signalling pathways and pathogen-related response (an American Ophthalmological Society thesis).

Authors: Harminder S Dua; Ahmad Muneer Otri; Andrew Hopkinson; Imran Mohammed
Journal: Trans Am Ophthalmol Soc Date: 2014-07

Focus on molecules: lacritin.

1. cDNA and genomic cloning of lacritin, a novel secretion enhancing factor from the human lacrimal gland.

2. Proteomic analysis of human meibomian gland secretions.

3. Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin.

4. Restricted epithelial proliferation by lacritin via PKCalpha-dependent NFAT and mTOR pathways.

1. Dry eye and designer ophthalmics.

Review 2. Antimicrobial compounds in tears.

3. In vitro studies on the antimicrobial peptide human beta-defensin 9 (HBD9): signalling pathways and pathogen-related response (an American Ophthalmological Society thesis).

4. Lacritin, a novel human tear glycoprotein, promotes sustained basal tearing and is well tolerated.

5. A thermo-responsive protein treatment for dry eyes.

Review 6. Lacritin and other new proteins of the lacrimal functional unit.

7. Lacritin rescues stressed epithelia via rapid forkhead box O3 (FOXO3)-associated autophagy that restores metabolism.

8. Development of a Quantitative Immunoassay for Tear Lacritin Proteoforms.