| Literature DB >> 1741062 |
P Sung1, L Prakash, S Prakash.
Abstract
The RAD10 gene of Saccharomyces cerevisiae is required for the incision step of excision repair of ultraviolet-damaged DNA, and it functions in mitotic recombination. RAD10 has homology to the human excision repair gene ERCC-1. Here we describe the purification of the protein encoded by RAD10 and show that it is a DNA-binding protein with a strong preference for single-stranded DNA. We also show that RAD10 promotes the renaturation of complementary DNA strands.Entities:
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Year: 1992 PMID: 1741062 DOI: 10.1038/355743a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962