Literature DB >> 17410003

Hedgehog signaling pathway and lung cancer.

Vamsidhar Velcheti1, Ramaswamy Govindan.   

Abstract

Signaling pathways responsible for embryogenesis play a critical role in the maintenance of stem cells in adult life and cellular responses to injury. Dysfunction of the developmental signaling pathways during adult homeostasis leads to various events resulting in the development of neoplasia. We review the biology of the hedgehog signaling pathway and its potential role in the development of lung cancer.

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Year:  2007        PMID： 17410003     DOI： 10.1097/JTO.0b013e31802c0276

Source DB:  PubMed          Journal:  J Thorac Oncol        ISSN： 1556-0864            Impact factor:   15.609


  27 in total

1.  Effects of the Hedgehog pathway inhibitor GDC-0449 on lung cancer cell lines are mediated by side populations.

Authors:  Fei Tian; Josef Mysliwietz; Joachim Ellwart; Fernando Gamarra; Rudolf Maria Huber; Albrecht Bergner
Journal:  Clin Exp Med       Date:  2011-04-26       Impact factor: 3.984

2.  Downregulation of hedgehog-interacting protein (HHIP) contributes to hexavalent chromium-induced malignant transformation of human bronchial epithelial cells.

Authors:  Peichao Li; Xiaoru Zhang; Anthony J Murphy; Max Costa; Xiaogang Zhao; Hong Sun
Journal:  Carcinogenesis       Date:  2021-02-11       Impact factor: 4.944

3.  Novel systemic therapies for small cell lung cancer.

Authors:  Charles M Rudin; Christine L Hann; Craig D Peacock; D Neil Watkins
Journal:  J Natl Compr Canc Netw       Date:  2008-03       Impact factor: 11.908

Review 4.  Small cell lung cancer: therapies and targets.

Authors:  Rathi N Pillai; Taofeek K Owonikoko
Journal:  Semin Oncol       Date:  2013-12-12       Impact factor: 4.929

5.  Zinc inhibits Hedgehog autoprocessing: linking zinc deficiency with Hedgehog activation.

Authors:  Jian Xie; Timothy Owen; Ke Xia; Ajay Vikram Singh; Emiley Tou; Lingyun Li; Brigitte Arduini; Hongmin Li; Leo Q Wan; Brian Callahan; Chunyu Wang
Journal:  J Biol Chem       Date:  2015-03-18       Impact factor: 5.157

6.  RACK1 promotes non-small-cell lung cancer tumorigenicity through activating sonic hedgehog signaling pathway.

Authors:  Shuo Shi; Yue-Zhen Deng; Jiang-Sha Zhao; Xiao-Dan Ji; Jun Shi; Yu-Xiong Feng; Guo Li; Jing-Jing Li; Di Zhu; H Phillip Koeffler; Yun Zhao; Dong Xie
Journal:  J Biol Chem       Date:  2012-01-19       Impact factor: 5.157

7.  Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer.

Authors:  Ke-Jie Chang; Meng-Hang Yang; Jin-Cheng Zheng; Bing Li; Wei Nie
Journal:  Am J Transl Res       Date:  2016-02-15       Impact factor: 4.060

8.  Hedgehog signaling pathway: the must, the maybe and the unknown.

Authors:  Paul Zarogoulidis; Katerina Zarampouka; Haidong Huang; Kaid Darwiche; Yong Huang; Antonis Sakkas; Konstantinos Zarogoulidis
Journal:  J Thorac Dis       Date:  2013-04       Impact factor: 2.895

9.  Activation of sonic hedgehog signaling pathway is an independent potential prognosis predictor in human hepatocellular carcinoma patients.

Authors:  Li Che; Yan-Hua Yuan; Jun Jia; Jun Ren
Journal:  Chin J Cancer Res       Date:  2012-12       Impact factor: 5.087

10.  Expression of Bmi1, FoxF1, Nanog, and γ-catenin in relation to hedgehog signaling pathway in human non-small-cell lung cancer.

Authors:  Ioannis P Gialmanidis; Vasiliki Bravou; Ilias Petrou; Helen Kourea; Alexandros Mathioudakis; Ioannis Lilis; Helen Papadaki
Journal:  Lung       Date:  2013-07-18       Impact factor: 2.584
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