| Literature DB >> 17409573 |
Krishna Prasad Devkota1, Muhammad Iqbal Choudhary, Sarfaraz Ahmed Nawaz, Alain Meli Lannang, Bruno Ndjakou Lenta, Patrice Aime Fokou, Norbert Sewald.
Abstract
The microbial transformation of a steroidal alkaloid, dictyophlebine (1) with Rhizopus stolonifer (ATCC 10404) afforded three oxidized metabolites 2-4. Compound 2 was found to be a new product. These metabolites were structurally characterized on the basis of modern spectroscopic techniques. Their inhibitory activity towards acetyl- and butyrylcholinesterase has been evaluated and the new product 2 has been found to be more potent than the parent compound and other metabolites.Entities:
Mesh：
Substances：
Year: 2007 PMID： 17409573 DOI： 10.1248/cpb.55.682
Source DB: PubMed Journal: Chem Pharm Bull (Tokyo) ISSN： 0009-2363 Impact factor: 1.645