Literature DB >> 17409221

Rational peptide selection to detect human immunodeficiency virus type 1-specific T-cell responses under resource-limited conditions.

C B Willberg1, S K Pillai, E R Sharp, M G Rosenberg, J D Agudelo, J D Barbour, D F Nixon.   

Abstract

Understanding human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T-lymphocyte responses is important for the development of vaccines and therapies. We describe a novel method for the rational selection of peptides that target stable regions of the HIV-1 genome, rich in epitopes specifically recognized by the study population. This method will be of particular use under resource/sample-limited conditions.

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Year:  2007        PMID： 17409221      PMCID： PMC1951093          DOI： 10.1128/CVI.00048-07

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN： 1556-679X


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