Literature DB >> 17409083

Survival quantitative trait locus fine mapping by measuring and testing for Hardy-Weinberg and linkage disequilibrium.

J Casellas1.   

Abstract

I show that fine-scale localization of a survival-related locus can be accomplished on the basis of deviations from Hardy-Weinberg equilibrium and linkage disequilibrium at closely linked marker loci. The method is based on chi(2)-tests and they can be performed for age-specific samples of alive (or dead) individuals, as for combined samples of alive and dead individuals.

Mesh：

Year:  2007        PMID： 17409083      PMCID： PMC1893058          DOI： 10.1534/genetics.106.067264

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  7 in total

1.  QTL fine mapping by measuring and testing for Hardy-Weinberg and linkage disequilibrium at a series of linked marker loci in extreme samples of populations.

Authors:  H W Deng; W M Chen; R R Recker
Journal:  Am J Hum Genet       Date:  2000-03       Impact factor: 11.025

2.  Robust indices of Hardy-Weinberg disequilibrium for QTL fine mapping.

Authors:  Hong-Wen Deng; Yu-Mei Li; Miao-Xin Li; Peng-Yuan Liu
Journal:  Hum Hered       Date:  2003       Impact factor: 0.444

3.  A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis.

Authors:  J N Feder; A Gnirke; W Thomas; Z Tsuchihashi; D A Ruddy; A Basava; F Dormishian; R Domingo; M C Ellis; A Fullan; L M Hinton; N L Jones; B E Kimmel; G S Kronmal; P Lauer; V K Lee; D B Loeb; F A Mapa; E McClelland; N C Meyer; G A Mintier; N Moeller; T Moore; E Morikang; C E Prass; L Quintana; S M Starnes; R C Schatzman; K J Brunke; D T Drayna; N J Risch; B R Bacon; R K Wolff
Journal:  Nat Genet       Date:  1996-08       Impact factor: 38.330

4.  Detecting marker-disease association by testing for Hardy-Weinberg disequilibrium at a marker locus.

Authors:  D M Nielsen; M G Ehm; B S Weir
Journal:  Am J Hum Genet       Date:  1998-11       Impact factor: 11.025

5.  Measuring the strength of associations between HLA antigens and diseases.

Authors:  B O Bengtsson; G Thomson
Journal:  Tissue Antigens       Date:  1981-11

6.  A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4.

Authors:  A A Puca; M J Daly; S J Brewster; T C Matise; J Barrett; M Shea-Drinkwater; S Kang; E Joyce; J Nicoli; E Benson; L M Kunkel; T Perls
Journal:  Proc Natl Acad Sci U S A       Date:  2001-08-27       Impact factor: 11.205

7.  Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM).

Authors:  R S Spielman; R E McGinnis; W J Ewens
Journal:  Am J Hum Genet       Date:  1993-03       Impact factor: 11.025
  7 in total
  2 in total

1.  A heterozygote-homozygote test of Hardy-Weinberg equilibrium.

Authors:  Jin J Zhou; Kenneth Lange; Jeanette C Papp; Janet S Sinsheimer
Journal:  Eur J Hum Genet       Date:  2009-04-15       Impact factor: 4.246

2.  A flexible bayesian model for testing for transmission ratio distortion.

Authors:  Joaquim Casellas; Arianna Manunza; Anna Mercader; Raquel Quintanilla; Marcel Amills
Journal:  Genetics       Date:  2014-09-29       Impact factor: 4.562
  2 in total

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