| Literature DB >> 17409008 |
Muazzam Jacobs1, Dieudonnée Togbe, Cecile Fremond, Arina Samarina, Nasiema Allie, Tania Botha, Daniela Carlos, Shreemanta K Parida, Sergei Grivennikov, Sergei Nedospasov, Analbery Monteiro, Marc Le Bert, Valerie Quesniaux, Bernhard Ryffel.
Abstract
Tumor necrosis factor (TNF) is critical and non-redundant to control Mycobacterium tuberculosis infection and cannot be replaced by other proinflammatory cytokines. Overproduction of TNF may cause immunopathology, while TNF neutralization reactivates latent and chronic, controlled infection, which is relevant for the use of neutralizing TNF therapies in patients with rheumatoid arthritis.Entities:
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Year: 2007 PMID： 17409008 DOI： 10.1016/j.micinf.2007.02.002
Source DB: PubMed Journal: Microbes Infect ISSN： 1286-4579 Impact factor: 2.700