| Literature DB >> 17408280 |
Muhammad I Javed1, Matthias Brewer.
Abstract
[reaction: see text] We report that "activated" dimethyl sulfoxide efficiently dehydrogenates hydrazones to the respective diazo species at -78 degrees C. Under optimized conditions, triethylamine hydrochloride is removed quantitatively by vacuum filtration to provide solutions of diazo compounds. Stable diazo species can be isolated in high yield, or alternatively, the direct treatment of these solutions with carboxylic acids provides esters.Entities:
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Year: 2007 PMID： 17408280 DOI： 10.1021/ol070515w
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005