Literature DB >> 17407102

GITR/GITRL: more than an effector T cell co-stimulatory system.

Giuseppe Nocentini1, Simona Ronchetti, Salvatore Cuzzocrea, Carlo Riccardi.   

Abstract

Glucocorticoid-induced TNFR-related protein (GITR) is a member of the TNFR superfamily, expressed in several cells and tissues including T lymphocytes, NK cells and antigen-presenting cells (APC). GITR activation, upon interaction with its ligand (GITRL), functions as a co-activating signal. GITRL is mainly expressed on APC and GITR/GITRL interaction is important for the development of immune response. This review summarizes recent results about the GITR/GITRL system, focusing on the interplay between APC, effector and regulatory T cells.

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Year:  2007        PMID： 17407102     DOI： 10.1002/eji.200636933

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  49 in total

Review 1.  Adaptive immune responses mediated by natural killer cells.

Authors:  Silke Paust; Balimkiz Senman; Ulrich H von Andrian
Journal:  Immunol Rev       Date:  2010-05       Impact factor: 12.988

2.  The glucocorticoid-induced TNF receptor family-related protein (GITR) is critical to the development of acute pancreatitis in mice.

Authors:  M Galuppo; G Nocentini; E Mazzon; S Ronchetti; E Esposito; L Riccardi; P Sportoletti; R Di Paola; S Bruscoli; C Riccardi; S Cuzzocrea
Journal:  Br J Pharmacol       Date:  2011-03       Impact factor: 8.739

Review 3.  Sequence, structure, function, immunity: structural genomics of costimulation.

Authors:  Kausik Chattopadhyay; Eszter Lazar-Molnar; Qingrong Yan; Rotem Rubinstein; Chenyang Zhan; Vladimir Vigdorovich; Udupi A Ramagopal; Jeffrey Bonanno; Stanley G Nathenson; Steven C Almo
Journal:  Immunol Rev       Date:  2009-05       Impact factor: 12.988

Review 4.  Natural killer cell memory.

Authors:  Silke Paust; Ulrich H von Andrian
Journal:  Nat Immunol       Date:  2011-06       Impact factor: 25.606

5.  Enhanced immune-modulatory effects of thalidomide and dexamethasone co-treatment on T cell subsets.

Authors:  Eun Jee Kim; Jae Geun Lee; Joon Ye Kim; Seung Hwan Song; Dong Jin Joo; Kyu Ha Huh; Myoung Soo Kim; Beom Seok Kim; Yu Seun Kim
Journal:  Immunology       Date:  2017-08-23       Impact factor: 7.397

6.  Systemic inflammatory response elicited by superantigen destabilizes T regulatory cells, rendering them ineffective during toxic shock syndrome.

Authors:  Ashenafi Y Tilahun; Vaidehi R Chowdhary; Chella S David; Govindarajan Rajagopalan
Journal:  J Immunol       Date:  2014-08-04       Impact factor: 5.422

7.  Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8 T-cells with cytotoxic as well as regulatory activity.

Authors:  Simone A Joosten; Krista E van Meijgaarden; Pascale C van Weeren; Fatima Kazi; Annemieke Geluk; Nigel D L Savage; Jan W Drijfhout; Darren R Flower; Willem A Hanekom; Michèl R Klein; Tom H M Ottenhoff
Journal:  PLoS Pathog       Date:  2010-02-26       Impact factor: 6.823

8.  Plasmodium vivax: induction of CD4+CD25+FoxP3+ regulatory T cells during infection are directly associated with level of circulating parasites.

Authors:  Lilian Lacerda Bueno; Cristiane Guimarães Morais; Fernanda Fortes Araújo; Juliana Assis Silva Gomes; Rodrigo Corrêa-Oliveira; Irene Silva Soares; Marcus Vinícius Lacerda; Ricardo Toshio Fujiwara; Erika Martins Braga
Journal:  PLoS One       Date:  2010-03-10       Impact factor: 3.240

Review 9.  Design of vaccine adjuvants incorporating TNF superfamily ligands and TNF superfamily molecular mimics.

Authors:  Sachin Gupta; James M Termini; Saravana Kanagavelu; Geoffrey W Stone
Journal:  Immunol Res       Date:  2013-12       Impact factor: 2.829

10.  1.8 A structure of murine GITR ligand dimer expressed in Drosophila melanogaster S2 cells.

Authors:  Kausik Chattopadhyay; Udupi A Ramagopal; Stanley G Nathenson; Steven C Almo
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2009-04-18
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