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Literature DB >> 17406578

Off-wafer fabrication and surface modification of asymmetric 3D SU-8 microparticles.

Sarah L Tao¹, Ketul Popat, Tejal A Desai.

Abstract

This protocol details a method of fabricating off-wafer, multilayered, asymmetric microparticles from the epoxy-based photosensitive polymer SU-8. Also included are methods for altering the surface properties of SU-8 and introducing functional groups for further covalent coupling reactions. These techniques may be used to create microparticles for applications in drug delivery and tissue engineering. Microparticle design, fabrication and surface modification can be completed in 2 d.

Entities: Chemical

Mesh：

Substances：

Year: 2006 PMID： 17406578 DOI： 10.1038/nprot.2006.451

Source DB: PubMed Journal: Nat Protoc ISSN： 1750-2799 Impact factor: 13.491

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Cited

16 in total

Review 1. Microfabrication technologies for oral drug delivery.

Authors: Shilpa Sant; Sarah L Tao; Omar Z Fisher; Qiaobing Xu; Nicholas A Peppas; Ali Khademhosseini
Journal: Adv Drug Deliv Rev Date: 2011-12-04 Impact factor: 15.470

Review 2. Designer nanoparticles: incorporating size, shape and triggered release into nanoscale drug carriers.

Authors: Mary Caldorera-Moore; Nathalie Guimard; Li Shi; Krishnendu Roy
Journal: Expert Opin Drug Deliv Date: 2010-04 Impact factor: 6.648

3. Microfabrication of an asymmetric, multi-layered microdevice for controlled release of orally delivered therapeutics.

Authors: Kristy M Ainslie; Casey M Kraning; Tejal A Desai
Journal: Lab Chip Date: 2008-05-16 Impact factor: 6.799

4. A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour.

Authors: Line Hagner Nielsen; Stephan Sylvest Keller; Anja Boisen; Anette Müllertz; Thomas Rades
Journal: Drug Deliv Transl Res Date: 2014-06 Impact factor: 4.617

5. Fabrication of micropatterned polymeric nanowire arrays for high-resolution reagent localization and topographical cellular control.

Authors: Cade B Fox; Jean Kim; Erica B Schlesinger; Hariharasudhan D Chirra; Tejal A Desai
Journal: Nano Lett Date: 2015-02-05 Impact factor: 11.189

Off-wafer fabrication and surface modification of asymmetric 3D SU-8 microparticles.

Review 1. Microfabrication technologies for oral drug delivery.

Review 2. Designer nanoparticles: incorporating size, shape and triggered release into nanoscale drug carriers.

3. Microfabrication of an asymmetric, multi-layered microdevice for controlled release of orally delivered therapeutics.

4. A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour.

5. Fabrication of micropatterned polymeric nanowire arrays for high-resolution reagent localization and topographical cellular control.

6. Planar microdevices for enhanced in vivo retention and oral bioavailability of poorly permeable drugs.

7. Multi-reservoir bioadhesive microdevices for independent rate-controlled delivery of multiple drugs.

Review 8. Physical approaches to biomaterial design.

Review 9. Emerging microtechnologies for the development of oral drug delivery devices.

Review 10. Planar bioadhesive microdevices: a new technology for oral drug delivery.