Literature DB >> 17405743

Two successful pregnancies in a chronic myeloid leukemia patient treated with imatinib.

Laurent Garderet1, Rodrigo Santacruz, Veronique Barbu, Jacqueline van den Akker, Bruno Carbonne, Norbert Claude Gorin.   

Abstract

The number of CML patients in child-bearing age and treated with imatinib is increasing. These women may want to be pregnant or are actually pregnant while on imatinib. Physicians do not know when to stop the treatment and what the risks are for the foetus and the mother. We report a case of a CML patient treated with imatinib who has two children, now 3 years and 10 months of age, in good health. The mother was in complete molecular remission, relapsed during pregnancy and reverted to remission in both cases after delivery.

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Year:  2007        PMID: 17405743     DOI: 10.3324/haematol.10935

Source DB:  PubMed          Journal:  Haematologica        ISSN: 0390-6078            Impact factor:   9.941


  6 in total

1.  Successful Pregnancy and Delivery in a Patient with Chronic Myeloid Leukemia while on Dasatinib Therapy.

Authors:  Monika Conchon; Sabri S Sanabani; Mariana Serpa; Mafalda M Y Novaes; Luciana Nardinelli; Patrícia B Ferreira; Pedro Enrique Dorliac-Llacer; Israel Bendit
Journal:  Adv Hematol       Date:  2010-03-07

2.  The impact of dasatinib on pregnancy outcomes.

Authors:  Jorge E Cortes; Elisabetta Abruzzese; Ekaterina Chelysheva; Mausumee Guha; Nicola Wallis; Jane F Apperley
Journal:  Am J Hematol       Date:  2015-10-12       Impact factor: 10.047

3.  A case of chronic myelogenous leukemia in pregnancy characterized by a complex translocation t(9;22;11)(q34;q11.2;q13).

Authors:  Surachit Kumar; Mariya Apostolova; Paul V Woolley
Journal:  Hematol Rep       Date:  2011-11-21

Review 4.  Tyrosine kinase inhibitors and pregnancy.

Authors:  Elisabetta Abruzzese; Malgorzata Monika Trawinska; Alessio Pio Perrotti; Paolo De Fabritiis
Journal:  Mediterr J Hematol Infect Dis       Date:  2014-04-07       Impact factor: 2.576

5.  The teratogenic effects of imatinib mesylate on rat fetuses.

Authors:  M M El Gendy; A M Kandil; M A Helal; F M Zahou
Journal:  Toxicol Rep       Date:  2015-05-11

6.  Pregnancy Outcomes in Chronic Myeloid Leukemia: A Single Center Experience.

Authors:  Irappa Madabhavi; Malay Sarkar; Mitul Modi; Nagaveni Kadakol
Journal:  J Glob Oncol       Date:  2019-09
  6 in total

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