Literature DB >> 17404934

Biotransformation of Cannabidiol to Cannabielsoin by Suspension Cultures of Cannabis sativa and Saccharum officinarum.

S C Hartsel1, W H Loh, L W Robertson.   

Abstract

Suspension cultures of CANNABIS SATIVA L. and SACCHARUM OFFICINARUM L. have been shown to biotransform cannabidiol to Cannabielsoin under normal growth conditions. Both Cannabielsoin C-1 stereoisomers were produced. Mass spectral and chromatographic evidence were used in this identification. This is the first reported biologically catalyzed synthesis of Cannabielsoin as well as the first biotransformation of any cannabinoid by plant tissue culture systems. Possible mechanisms and significance of this conversion are discussed.

Entities:  

Year:  1983        PMID： 17404934     DOI： 10.1055/s-2007-969870

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  7 in total

1.  Cannabis 25 (1), biotransformation of cannabidiol and cannabidiolic acid by Pinellia ternata tissue segments.

Authors:  H Tanaka; R Takahashi; S Morimoto; Y Shoyama
Journal:  Plant Cell Rep       Date:  1996-08       Impact factor: 4.570

2.  Biotransformation of cannabinoids by a cell suspension culture of Cannabis sativa L.

Authors:  R Braemer; M Paris
Journal:  Plant Cell Rep       Date:  1987-04       Impact factor: 4.570

Review 3.  Molecular Targets of the Phytocannabinoids: A Complex Picture.

Authors:  Paula Morales; Dow P Hurst; Patricia H Reggio
Journal:  Prog Chem Org Nat Prod       Date:  2017

Review 4.  An Overview on Medicinal Chemistry of Synthetic and Natural Derivatives of Cannabidiol.

Authors:  Paula Morales; Patricia H Reggio; Nadine Jagerovic
Journal:  Front Pharmacol       Date:  2017-06-28       Impact factor: 5.810

Review 5.  Designing microorganisms for heterologous biosynthesis of cannabinoids.

Authors:  Ângela Carvalho; Esben Halkjær Hansen; Oliver Kayser; Simon Carlsen; Felix Stehle
Journal:  FEMS Yeast Res       Date:  2017-06-01       Impact factor: 2.796

Review 6.  Advances and Perspectives in Tissue Culture and Genetic Engineering of Cannabis.

Authors:  Mohsen Hesami; Austin Baiton; Milad Alizadeh; Marco Pepe; Davoud Torkamaneh; Andrew Maxwell Phineas Jones
Journal:  Int J Mol Sci       Date:  2021-05-26       Impact factor: 5.923

Review 7.  Human Metabolites of Cannabidiol: A Review on Their Formation, Biological Activity, and Relevance in Therapy.

Authors:  István Ujváry; Lumír Hanuš
Journal:  Cannabis Cannabinoid Res       Date:  2016-03-01
  7 in total

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