| Literature DB >> 17404605 |
Seong-Tae Han1, Robert G Griffin, Kan-Nian Hu, Chan-Gyu Joo, Colin D Joye, Ivan Mastovsky, Michael A Shapiro, Jagadishwar R Sirigiri, Richard J Temkin, Antonio C Torrezan, Paul P Woskov.
Abstract
Recently, dynamic nuclear polarization enhanced nuclear magnetic resonance (DNP/NMR) has emerged as a powerful technique to obtain significant enhancements in spin spectra from biological samples. For DNP in modern NMR systems, a high power continuous-wave source in the submillimeter wavelength range is necessary. Gyrotrons can deliver tens of watts of CW power at submillimeter wavelengths and are well suited for use in DNP/NMR spectrometers. To date, 140 GHz and 250 GHz gyrotrons are being employed in DNP spectrometer experiments at 200 MHz and 380 MHz at MIT. A 460 GHz gyrotron, which has operated with 8 W of CW output power, will soon be installed in a 700 MHz NMR spectrometer. High power radiation with good spectral and spatial resolution from these gyrotrons should provide NMR spectrometers with high signal enhancement through DNP. Also, these tubes operating at submillimeter wavelengths should have important applications in research in physics, chemistry, biology, materials science and medicine.Entities:
Year: 2006 PMID: 17404605 PMCID: PMC1847421 DOI: 10.1117/12.686436
Source DB: PubMed Journal: Proc SPIE Int Soc Opt Eng ISSN: 0277-786X