Literature DB >> 17403485

Broncholith caused by donor-acquired histoplasmosis in a lung transplant recipient.

Sonia S Shah1, Demet Karnak, Shetal N Shah, Marie Budev, Michael Machuzak, Thomas R Gildea, Atul C Mehta.   

Abstract

A broncholith is a calcified lymph node that erodes into and partially or completely obstructs the bronchial lumen. The natural history of broncholiths is poorly understood. They are frequently encountered in residents of areas that are endemic for Histoplasma capsulatum and Mycobacterium tuberculum. We report the first case of a broncholith in which the fungus Histoplasma capsulatum was transferred from a donor to a lung transplant (LTx) recipient. Our report highlights the time course of broncholith development and its successful management. We suspect that broncholithiasis and transmission of Histoplasma capsulatum from a donor to the recipient are under-reported in the LTx literature. We hypothesize that histoplasmosis can be transmitted from the donor to the recipient and the duration in the formation of calcification of the lymph node or the broncholith can be anywhere from 2 to 10 months.

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Year:  2007        PMID: 17403485     DOI: 10.1016/j.healun.2007.01.014

Source DB:  PubMed          Journal:  J Heart Lung Transplant        ISSN: 1053-2498            Impact factor:   10.247


  2 in total

1.  Cutaneous and bone marrow histoplasmosis after 18 years of renal allograft transplant.

Authors:  K Y Ibrahim; N B Carvalho; E V Mimicos; H Yeh-Li; M N Sotto; F O S França
Journal:  Mycopathologia       Date:  2014-08-06       Impact factor: 2.574

2.  Disseminated Histoplasmosis Presenting as Acute Respiratory Distress Syndrome and Disseminated Intravascular Coagulation in an HIV Positive Immigrant from Central America.

Authors:  Ramakanth Pata; Nway Nway; Innocent Lutaya; Victor Chen
Journal:  Cureus       Date:  2022-02-05
  2 in total

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