Literature DB >> 17403440

Oral contraceptive discontinuation: do side effects matter?

Carolyn L Westhoff1, Stephen Heartwell, Sharon Edwards, Mimi Zieman, Gretchen Stuart, Carrie Cwiak, Anne Davis, Tina Robilotto, Linda Cushman, Debra Kalmuss.   

Abstract

OBJECTIVE: The purpose of this study was to assess self-reported side effects in women after they received the oral contraceptive (OC) and to compare discontinuation rates, according to presence or absence of side effects. STUDY
DESIGN: The study comprised 1716 women aged <25 years who initiated the OC at 3 publicly funded family planning clinics and completed structured interviews after 3 and 6 months.
RESULTS: Nearly 60% of subjects discontinued the OC by 6 months. Most subjects reported no changes in headaches, weight, moodiness, and sexual satisfaction during the first 3 months of OC use. Subjects with any complaints, especially women with increased headaches or moodiness, were more likely to discontinue the OC prematurely. Nonetheless, most discontinuation occurred for reasons that were unrelated to side effects.
CONCLUSION: Side effects are absent or mild among most OC users, but women with complaints are more likely to discontinue. Side effects are less important reasons for discontinuation than widely believed.

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Year:  2007        PMID: 17403440      PMCID: PMC1903378          DOI: 10.1016/j.ajog.2006.12.015

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  9 in total

Review 1.  Adherence to medication.

Authors:  Lars Osterberg; Terrence Blaschke
Journal:  N Engl J Med       Date:  2005-08-04       Impact factor: 91.245

2.  Fertility, family planning, and women's health: new data from the 1995 National Survey of Family Growth.

Authors:  J C Abma; A Chandra; W D Mosher; L S Peterson; L J Piccinino
Journal:  Vital Health Stat 23       Date:  1997-05

3.  Oral contraceptive pill use after an initial visit to a family planning clinic.

Authors:  D Oakley; S Sereika; E L Bogue
Journal:  Fam Plann Perspect       Date:  1991 Jul-Aug

4.  Oral contraceptive discontinuation: a prospective evaluation of frequency and reasons.

Authors:  M J Rosenberg; M S Waugh
Journal:  Am J Obstet Gynecol       Date:  1998-09       Impact factor: 8.661

5.  Contraceptive use among adolescent mothers at 6 months postpartum.

Authors:  A B Berenson; C M Wiemann
Journal:  Obstet Gynecol       Date:  1997-06       Impact factor: 7.661

6.  Adolescents' compliance with the use of oral contraceptives.

Authors:  S J Emans; E Grace; E R Woods; D E Smith; K Klein; J Merola
Journal:  JAMA       Date:  1987-06-26       Impact factor: 56.272

7.  Quick start: novel oral contraceptive initiation method.

Authors:  Carolyn Westhoff; Jennifer Kerns; Chelsea Morroni; Linda F Cushman; Lorraine Tiezzi; Patricia Aikins Murphy
Journal:  Contraception       Date:  2002-09       Impact factor: 3.375

8.  Bleeding patterns after immediate vs. conventional oral contraceptive initiation: a randomized, controlled trial.

Authors:  Carolyn Westhoff; Chelsea Morroni; Jennifer Kerns; Patricia Aikins Murphy
Journal:  Fertil Steril       Date:  2003-02       Impact factor: 7.329

9.  Use and misuse of oral contraceptives: risk indicators for poor pill taking and discontinuation.

Authors:  M J Rosenberg; M S Waugh; T E Meehan
Journal:  Contraception       Date:  1995-05       Impact factor: 3.375

  9 in total
  35 in total

1.  Hormonal contraceptive users' self-reported benefits, adverse reactions, and fears in 2001 and 2007.

Authors:  Miia Tiihonen; Hanna-Mari Leppänen; Anna-Mari Heikkinen; Riitta Ahonen
Journal:  Patient       Date:  2008-07-01       Impact factor: 3.883

2.  Oral contraceptive use and depression among adolescents.

Authors:  Sarah McKetta; Katherine M Keyes
Journal:  Ann Epidemiol       Date:  2018-10-13       Impact factor: 3.797

Review 3.  The Sexual Acceptability of Contraception: Reviewing the Literature and Building a New Concept.

Authors:  Jenny A Higgins; Nicole K Smith
Journal:  J Sex Res       Date:  2016-03-08

4.  Continuation of prescribed compared with over-the-counter oral contraceptives.

Authors:  Joseph E Potter; Sarah McKinnon; Kristine Hopkins; Jon Amastae; Michele G Shedlin; Daniel A Powers; Daniel Grossman
Journal:  Obstet Gynecol       Date:  2011-03       Impact factor: 7.661

5.  Association of Use of Oral Contraceptives With Depressive Symptoms Among Adolescents and Young Women.

Authors:  Anouk E de Wit; Sanne H Booij; Erik J Giltay; Hadine Joffe; Robert A Schoevers; Albertine J Oldehinkel
Journal:  JAMA Psychiatry       Date:  2020-01-01       Impact factor: 21.596

6.  Oral contraceptive use and psychiatric disorders in a nationally representative sample of women.

Authors:  Keely Cheslack-Postava; Katherine M Keyes; Sarah R Lowe; Karestan C Koenen
Journal:  Arch Womens Ment Health       Date:  2014-08-13       Impact factor: 3.633

Review 7.  Progesterone, reproduction, and psychiatric illness.

Authors:  Lindsay R Standeven; Katherine O McEvoy; Lauren M Osborne
Journal:  Best Pract Res Clin Obstet Gynaecol       Date:  2020-06-18       Impact factor: 5.237

8.  Weight and body composition changes during oral contraceptive use in obese and normal weight women.

Authors:  Elizabeth R Mayeda; Anupama H Torgal; Carolyn L Westhoff
Journal:  J Womens Health (Larchmt)       Date:  2013-10-24       Impact factor: 2.681

9.  Association of hormonal contraceptive use with reduced levels of depressive symptoms: a national study of sexually active women in the United States.

Authors:  Katherine M Keyes; Keely Cheslack-Postava; Carolyn Westhoff; Christine M Heim; Michelle Haloossim; Kate Walsh; Karestan Koenen
Journal:  Am J Epidemiol       Date:  2013-09-15       Impact factor: 4.897

10.  The influence of oral contraceptive knowledge on oral contraceptive continuation among young women.

Authors:  Kelli Stidham Hall; Paula M Castaño; Carolyn L Westhoff
Journal:  J Womens Health (Larchmt)       Date:  2014-02-26       Impact factor: 2.681

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