PURPOSE: To report the clinical features of eight patients presenting with emulsification of the heavier than water vitreous substitute, Densiron-68. METHODS: Two patients underwent primary inferior retinal detachment (RD) surgery, two patients underwent giant retinal tear repair, three patients had repair of inferior RD complicated by proliferative vitreoretinopathy and one patient had inferior RD surgery following repair of a scleral rupture. All patients had insertion of Densiron-68. RESULTS: Significant emulsification of Densiron-68 was seen within 12 weeks of surgery in eight cases out of a total of 40 patients receiving Densiron-68. CONCLUSION: Despite adequate Densiron fills, emulsification necessitated its removal. Emulsified Densiron may have contributed to significant intraocular inflammation, epiretinal membrane formation and cystoid macular oedema. Without removal, prolonged presence of emulsified Densiron may lead to keratopathy, secondary glaucoma and retinal toxicity secondary to partitioning of perfluorohexyloctane. This has potentially significant implications on the indications for Densiron-68 use and warrants consideration before deciding on the optimal surgical intervention for inferior RDs.
PURPOSE: To report the clinical features of eight patients presenting with emulsification of the heavier than water vitreous substitute, Densiron-68. METHODS: Two patients underwent primary inferior retinal detachment (RD) surgery, two patients underwent giant retinal tear repair, three patients had repair of inferior RD complicated by proliferative vitreoretinopathy and one patient had inferior RD surgery following repair of a scleral rupture. All patients had insertion of Densiron-68. RESULTS: Significant emulsification of Densiron-68 was seen within 12 weeks of surgery in eight cases out of a total of 40 patients receiving Densiron-68. CONCLUSION: Despite adequate Densiron fills, emulsification necessitated its removal. Emulsified Densiron may have contributed to significant intraocular inflammation, epiretinal membrane formation and cystoid macular oedema. Without removal, prolonged presence of emulsified Densiron may lead to keratopathy, secondary glaucoma and retinal toxicity secondary to partitioning of perfluorohexyloctane. This has potentially significant implications on the indications for Densiron-68 use and warrants consideration before deciding on the optimal surgical intervention for inferior RDs.
Authors: M R Romano; T Stappler; J Marticorena; C Groenewald; I Pearce; S K Gibran; D Wong; H Heimann Journal: Graefes Arch Clin Exp Ophthalmol Date: 2008-07-11 Impact factor: 3.117
Authors: Francesco Morescalchi; Ciro Costagliola; Sarah Duse; Elena Gambicorti; Barbara Parolini; Barbara Arcidiacono; Mario R Romano; Francesco Semeraro Journal: Biomed Res Int Date: 2014-07-08 Impact factor: 3.411
Authors: Peijuan Wang; Qianying Gao; Xiaofeng Lin; Shaochong Zhang; Jie Hu; Yaqin Liu; Nuo Xu; Jian Ge Journal: PLoS One Date: 2012-10-01 Impact factor: 3.240