| Literature DB >> 17401163 |
Angela N Cauthen1, Amanda R Welton, Katherine R Spindler.
Abstract
Mouse adenovirus provides a model for studying adenovirus pathogenesis in the natural host. The ability to make viral mutants allows the investigation of specific mouse adenoviral gene contributions to virus-host interactions. Methods for propagation and titration of wild-type mouse adenovirus, production of viral DNA and viral DNA-protein complex, and transfection of mouse cells to obtain mouse adenovirus mutants are described in this chapter. Plaque purification, propagation, and titration of the mutant viruses are also presented.Entities:
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Year: 2007 PMID： 17401163 DOI： 10.1385/1-59745-166-5:41
Source DB: PubMed Journal: Methods Mol Med ISSN： 1543-1894