Literature DB >> 17397637

[Are benzodiazepines correctly used in the elderly?].

T Barberá1, J A Avellana, L Moreno.   

Abstract

Benzodiazepines are substances susceptible of producing drug dependence in addition to tolerability to sedative effects and frequent interactions when associated with other drugs. Thus, use of long half life benzodiazepines and inadequate intermediate and short half life dosage is related with falls and fractures in elderly patients. A retrospective study was conducted on the official prescriptions made during 2000-2003 and the daily dose defined per thousand patients/day (DDD/I) was used as a measurement of drug consumption. Prescription of benzodiazepines that are eliminated by oxidative metabolism should be revaluated and modified by other of conjunctive metabolism when treating elderly patients to decrease adverse reactions such as excess sedation, risk of falls and associated fractures.

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Year:  2007        PMID: 17397637     DOI: 10.1157/13100229

Source DB:  PubMed          Journal:  Rev Clin Esp        ISSN: 0014-2565            Impact factor:   1.556


  2 in total

Review 1.  The clinical implications of ageing for rational drug therapy.

Authors:  Shaojun Shi; Klaus Mörike; Ulrich Klotz
Journal:  Eur J Clin Pharmacol       Date:  2008-01-05       Impact factor: 2.953

2.  Potentially inappropriate prescribing in institutionalised older patients in Spain: the STOPP-START criteria compared with the Beers criteria.

Authors:  Amalia Ubeda; Luisa Ferrándiz; Nuria Maicas; Cristina Gomez; Montserrat Bonet; Jose E Peris
Journal:  Pharm Pract (Granada)       Date:  2012-06-30
  2 in total

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