Literature DB >> 17396075

Is it a pheochromocytoma?

Joel Handler1.   

Abstract

The patient is a 44-year-old man with a 4-year history of intermittently elevated blood pressure (BP) controlled by diet and exercise. Three months before evaluation he described daily "spikes" of BP with sharp unilateral headaches. He was seen in the emergency department with a BP of 212/106 mm Hg and was started on hydrochlorothiazide 25 mg daily. He denied palpitations, diaphoretic episodes, pallor, and tremor. The patient did not want to take medication and specifically requested an evaluation to rule out pheochromocytoma. Results from 24-hour urine tests for total metanephrines was 812 mg/24 h (normal, 130-520 mg/24 h), for total catecholamines was 53 mg/24 h (normal, 0-135 mg/24 h), and for vanillylmandelic acid was 4.7 mg/24 h (normal, <7 mg/24 h). Thyroid-stimulating hormone was 0.87 (normal, 0.4-4.0 IU/mL). Physical examination revealed normal optic fundi, negative cardiac examination results, and presence of peripheral pulses without bruits. His BP was now 136/74 mm Hg, with a heart rate of 76 beats per minute.

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Year:  2007        PMID: 17396075      PMCID: PMC8110102          DOI: 10.1111/j.1524-6175.2007.06551.x

Source DB:  PubMed          Journal:  J Clin Hypertens (Greenwich)        ISSN: 1524-6175            Impact factor:   3.738


  16 in total

Review 1.  Severe paroxysmal hypertension (pseudopheochromocytoma): understanding the cause and treatment.

Authors:  S J Mann
Journal:  Arch Intern Med       Date:  1999-04-12

Review 2.  Editorial: biochemical diagnosis of pheochromocytoma--is it time to switch to plasma-free metanephrines?

Authors:  Graeme Eisenhofer
Journal:  J Clin Endocrinol Metab       Date:  2003-02       Impact factor: 5.958

Review 3.  Clinical review 164: The laboratory diagnosis of adrenal pheochromocytoma: the Mayo Clinic experience.

Authors:  Yogish C Kudva; Anna M Sawka; William F Young
Journal:  J Clin Endocrinol Metab       Date:  2003-10       Impact factor: 5.958

4.  Interpreting hoofbeats: can Bayes help clear the haze?

Authors:  S G Pauker; R I Kopelman
Journal:  N Engl J Med       Date:  1992-10-01       Impact factor: 91.245

5.  De subitaneis mortibus. XIX. On the cause of sudden death in pheochromocytoma, with special reference to the pulmonary arteries, the cardiac conduction system, and the aggregation of platelets.

Authors:  T N James
Journal:  Circulation       Date:  1976-08       Impact factor: 29.690

Review 6.  Pheochromocytoma: diagnosis and management update.

Authors:  William M Manger; Graeme Eisenhofer
Journal:  Curr Hypertens Rep       Date:  2004-12       Impact factor: 5.369

7.  Daily life blood pressure changes are steeper in hypertensive than in normotensive subjects.

Authors:  Giuseppe Mancia; Gianfranco Parati; Paolo Castiglioni; Roberto Tordi; Elena Tortorici; Fabio Glavina; Marco Di Rienzo
Journal:  Hypertension       Date:  2003-07-28       Impact factor: 10.190

8.  The economic implications of three biochemical screening algorithms for pheochromocytoma.

Authors:  Anna M Sawka; Amiram Gafni; Lehana Thabane; William F Young
Journal:  J Clin Endocrinol Metab       Date:  2004-06       Impact factor: 5.958

9.  Diagnosis and localization of pheochromocytoma.

Authors:  David S Goldstein; Graeme Eisenhofer; John A Flynn; Gary Wand; Karel Pacak
Journal:  Hypertension       Date:  2004-03-15       Impact factor: 10.190

Review 10.  Pheochromocytoma.

Authors:  William M Manger; Ray W Gifford
Journal:  J Clin Hypertens (Greenwich)       Date:  2002 Jan-Feb       Impact factor: 3.738

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  1 in total

1.  Nonfunctioning benign cardiac pheochromocytoma.

Authors:  Qingbao Li; Quanxin Fan; Decai Li; Haizhou Zhang
Journal:  J Cancer Res Clin Oncol       Date:  2008-06-19       Impact factor: 4.553

  1 in total

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