Literature DB >> 1739428

Helix-loop-helix proteins in the regulation of immunoglobulin gene transcription.

T Kadesch1.   

Abstract

Transcriptional control of the Ig heavy chain and kappa light chain is dominated by single enhancers located within the body of each gene. These enhancers bind distinct, yet overlapping, sets of cell-type-specific and ubiquitous nuclear proteins. This review focuses on one particular subclass of enhancer-binding protein, termed helix-loop-helix (HLH) proteins, describing their role in the establishment of cell-type-specific transcription and suggesting how they may be regulated during B-cell maturation.

Mesh：

Substances：

Year:  1992        PMID： 1739428     DOI： 10.1016/0167-5699(92)90201-h

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  42 in total

1.  Transcriptional activation by ETS and leucine zipper-containing basic helix-loop-helix proteins.

Authors:  G Tian; B Erman; H Ishii; S S Gangopadhyay; R Sen
Journal:  Mol Cell Biol       Date:  1999-04       Impact factor: 4.272

2.  Characterization of the human immunoglobulin kappa gene 3' enhancer: functional importance of three motifs that demonstrate B-cell-specific in vivo footprints.

Authors:  J G Judde; E E Max
Journal:  Mol Cell Biol       Date:  1992-11       Impact factor: 4.272

3.  E47 phosphorylation by p38 MAPK promotes MyoD/E47 association and muscle-specific gene transcription.

Authors:  Frederic Lluís; Esteban Ballestar; Mònica Suelves; Manel Esteller; Pura Muñoz-Cánoves
Journal:  EMBO J       Date:  2005-02-17       Impact factor: 11.598

4.  An HLA-B regulatory element binds a factor immunologically related to the upstream stimulation factor.

Authors:  J Girdlestone
Journal:  Immunogenetics       Date:  1993       Impact factor: 2.846

5.  Transrepression of lck gene expression by human T-cell leukemia virus type 1-encoded p40tax.

Authors:  I Lemasson; V Robert-Hebmann; S Hamaia; M Duc Dodon; L Gazzolo; C Devaux
Journal:  J Virol       Date:  1997-03       Impact factor: 5.103

6.  ETS-mediated cooperation between basic helix-loop-helix motifs of the immunoglobulin mu heavy-chain gene enhancer.

Authors:  W Dang; X H Sun; R Sen
Journal:  Mol Cell Biol       Date:  1998-03       Impact factor: 4.272

7.  Flanking sequences modulate the cell specificity of M-CAT elements.

Authors:  S B Larkin; I K Farrance; C P Ordahl
Journal:  Mol Cell Biol       Date:  1996-07       Impact factor: 4.272

8.  Differences between MyoD DNA binding and activation site requirements revealed by functional random sequence selection.

Authors:  J Huang; T K Blackwell; L Kedes; H Weintraub
Journal:  Mol Cell Biol       Date:  1996-07       Impact factor: 4.272

9.  Pathogenic determinants in the U3 region of recombinant murine leukemia viruses isolated from CWD and HRS/J mice.

Authors:  S C Lawrenz-Smith; A C Massey; D J Innes; C Y Thomas
Journal:  J Virol       Date:  1994-08       Impact factor: 5.103

10.  B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.

Authors:  Y Zhuang; P Cheng; H Weintraub
Journal:  Mol Cell Biol       Date:  1996-06       Impact factor: 4.272
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.