Literature DB >> 17394018

A strong association between human earwax-type and apocrine colostrum secretion from the mammary gland.

Kiyonori Miura1, Koh-ichiro Yoshiura, Shoko Miura, Takako Shimada, Kentaro Yamasaki, Atsushi Yoshida, Daisuke Nakayama, Yoshisada Shibata, Norio Niikawa, Hideaki Masuzaki.   

Abstract

Here we provided the first genetic evidence for an association between the degree of apocrine colostrum secretion and human earwax type. Genotyping at the earwax-type locus, rs17822931 within the ABCC11 gene, revealed that 155 of 225 Japanese women were dry-type and 70 wet-type. Frequency of women without colostrum among dry-type women was significantly higher than that among wet-type women (P<0.0002), and the measurable colostrum volume in dry-type women was significantly smaller than in wet-type women (P=0.0341).

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Year:  2007        PMID： 17394018     DOI： 10.1007/s00439-007-0356-9

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  5 in total

1.  An alpha(2)-globulin component present in sweat, saliva, tears, human milk, colostrum and cerumen.

Authors:  M Jirka
Journal:  FEBS Lett       Date:  1968-07       Impact factor: 4.124

2.  Association of race, age, menopausal status, and cerumen type with breast fluid secretion in nonlactating women, as determined by nepple aspiration.

Authors:  N L Petrakis; L Mason; R Lee; B Sugimoto; S Pawson; F Catchpool
Journal:  J Natl Cancer Inst       Date:  1975-04       Impact factor: 13.506

3.  Cerumen phenotype and proliferative epithelium in breast fluids of U.S.-born vs. immigrant Asian women: a possible genetic-environmental interaction.

Authors:  N L Petrakis; E B King; M Lee; R Miike
Journal:  Breast Cancer Res Treat       Date:  1990-10       Impact factor: 4.872

4.  A SNP in the ABCC11 gene is the determinant of human earwax type.

Authors:  Koh-ichiro Yoshiura; Akira Kinoshita; Takafumi Ishida; Aya Ninokata; Toshihisa Ishikawa; Tadashi Kaname; Makoto Bannai; Katsushi Tokunaga; Shunro Sonoda; Ryoichi Komaki; Makoto Ihara; Vladimir A Saenko; Gabit K Alipov; Ichiro Sekine; Kazuki Komatsu; Haruo Takahashi; Mitsuko Nakashima; Nadiya Sosonkina; Christophe K Mapendano; Mohsen Ghadami; Masayo Nomura; De-Sheng Liang; Nobutomo Miwa; Dae-Kwang Kim; Ariuntuul Garidkhuu; Nagato Natsume; Tohru Ohta; Hiroaki Tomita; Akira Kaneko; Mihoko Kikuchi; Graciela Russomando; Kenji Hirayama; Minaka Ishibashi; Aya Takahashi; Naruya Saitou; Jeffery C Murray; Susumu Saito; Yusuke Nakamura; Norio Niikawa
Journal:  Nat Genet       Date:  2006-01-29       Impact factor: 38.330

5.  MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine.

Authors:  Yanping Guo; Elena Kotova; Zhe-Sheng Chen; Kun Lee; Elizabeth Hopper-Borge; Martin G Belinsky; Gary D Kruh
Journal:  J Biol Chem       Date:  2003-05-22       Impact factor: 5.157
  5 in total
  15 in total

1.  Strong association of the SNP rs17822931 with wet earwax and bromhidrosis in a Chinese family.

Authors:  Dandan Shang; Xue Zhang; Miao Sun; Yang Wei; Yaran Wen
Journal:  J Genet       Date:  2013       Impact factor: 1.166

Review 2.  Multidrug resistance proteins (MRPs/ABCCs) in cancer chemotherapy and genetic diseases.

Authors:  Zhe-Sheng Chen; Amit K Tiwari
Journal:  FEBS J       Date:  2011-08-01       Impact factor: 5.542

Review 3.  Redox regulation of multidrug resistance in cancer chemotherapy: molecular mechanisms and therapeutic opportunities.

Authors:  Macus Tien Kuo
Journal:  Antioxid Redox Signal       Date:  2009-01       Impact factor: 8.401

Review 4.  Xenobiotic, bile acid, and cholesterol transporters: function and regulation.

Authors:  Curtis D Klaassen; Lauren M Aleksunes
Journal:  Pharmacol Rev       Date:  2010-01-26       Impact factor: 25.468

Review 5.  Pharmacogenomics of human ABC transporter ABCC11 (MRP8): potential risk of breast cancer and chemotherapy failure.

Authors:  Yu Toyoda; Toshihisa Ishikawa
Journal:  Anticancer Agents Med Chem       Date:  2010-10-01       Impact factor: 2.505

6.  Enhanced Edar signalling has pleiotropic effects on craniofacial and cutaneous glands.

Authors:  Shie Hong Chang; Stephanie Jobling; Keith Brennan; Denis J Headon
Journal:  PLoS One       Date:  2009-10-26       Impact factor: 3.240

7.  Localization of putative binding sites for cyclic guanosine monophosphate and the anti-cancer drug 5-fluoro-2'-deoxyuridine-5'-monophosphate on ABCC11 in silico models.

Authors:  Mylène Honorat; Raphaël Terreux; Pierre Falson; Attilio Di Pietro; Charles Dumontet; Lea Payen
Journal:  BMC Struct Biol       Date:  2013-05-06

8.  Dependence of deodorant usage on ABCC11 genotype: scope for personalized genetics in personal hygiene.

Authors:  Santiago Rodriguez; Colin D Steer; Alexandra Farrow; Jean Golding; Ian N M Day
Journal:  J Invest Dermatol       Date:  2013-01-17       Impact factor: 8.551

9.  Pharmacogenetics of human ABC transporter ABCC11: new insights into apocrine gland growth and metabolite secretion.

Authors:  Toshihisa Ishikawa; Yu Toyoda; Koh-Ichiro Yoshiura; Norio Niikawa
Journal:  Front Genet       Date:  2013-01-02       Impact factor: 4.599

10.  Haplotype-assisted accurate non-invasive fetal whole genome recovery through maternal plasma sequencing.

Authors:  Shengpei Chen; Huijuan Ge; Xuebin Wang; Xiaoyu Pan; Xiaotian Yao; Xuchao Li; Chunlei Zhang; Fang Chen; Fuman Jiang; Peipei Li; Hui Jiang; Hancheng Zheng; Lei Zhang; Lijian Zhao; Wei Wang; Songgang Li; Jun Wang; Jian Wang; Huanming Yang; Yingrui Li; Xiuqing Zhang
Journal:  Genome Med       Date:  2013-02-27       Impact factor: 11.117
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