Literature DB >> 17393653

Two new chemical constituents from Daphne odora Thunb. var. marginata.

W Zhang1, W D Zhang, R H Liu, Y H Shen, C Zhang, H S Cheng, P Fu, L Shan.   

Abstract

Two new phenolic constituents, daphnenone (1) and daphneone (2), were isolated from the stem bark of Daphne odora Thunb. var. marginata. Their structures were established on the basis of spectroscopic analysis. Compounds 1 and 2 were tested for cytotoxic activity by MTT assays on five human tumour cell lines, K562, A549, MCF-7, LOVO and HepG2. Compound 1 showed obvious cytotoxic activity against all the five cell lines.

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Year:  2006        PMID: 17393653     DOI: 10.1080/14786410601101860

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN: 1478-6419            Impact factor:   2.861


  2 in total

1.  Discovery of Natural Products as Novel and Potent FXR Antagonists by Virtual Screening.

Authors:  Yanyan Diao; Jing Jiang; Shoude Zhang; Shiliang Li; Lei Shan; Jin Huang; Weidong Zhang; Honglin Li
Journal:  Front Chem       Date:  2018-04-30       Impact factor: 5.221

2.  Effects of an ethyl acetate extract of Daphne altaica stem bark on the cell cycle, apoptosis and expression of PPARγ in Eca‑109 human esophageal carcinoma cells.

Authors:  Murat Kizaibek; Ayixiamuguli Wubuli; Zhengbing Gu; Didar Bahetjan; Lazzat Tursinbai; Kamishbek Nurhamit; Bin Chen; Jing Wang; Omirshat Tahan; Peng Cao
Journal:  Mol Med Rep       Date:  2020-05-27       Impact factor: 2.952

  2 in total

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