Literature DB >> 17393583

Linking the epigenetic 'language' of covalent histone modifications to cancer.

S B Hake1, A Xiao, C D Allis.   

Abstract

Covalent modifications of histones, such as acetylation, methylation, and phosphorylation, and other epigenetic modulations of the chromatin, such as methylation of DNA and ATP-dependent chromatin reorganisation, can play a major part in the multistep process of carcinogenesis, with far-reaching implications for human biology and human health. This review focuses on how aberrant covalent histone modifications may contribute to the development of a variety of human cancers, and discusses the recent findings with regard to potential therapies.

Entities:  

Year:  2007        PMID： 17393583

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  16 in total

1.  Arsenic induces polyadenylation of canonical histone mRNA by down-regulating stem-loop-binding protein gene expression.

Authors:  Jason Brocato; Lei Fang; Yana Chervona; Danqi Chen; Kathrin Kiok; Hong Sun; Hsiang-Chi Tseng; Dazhong Xu; Magdy Shamy; Chunyuan Jin; Max Costa
Journal:  J Biol Chem       Date:  2014-09-28       Impact factor: 5.157

2.  Identification of a functional network of human epigenetic silencing factors.

Authors:  Andrey Poleshko; Margret B Einarson; Natalia Shalginskikh; Rugang Zhang; Peter D Adams; Anna Marie Skalka; Richard A Katz
Journal:  J Biol Chem       Date:  2009-10-30       Impact factor: 5.157

3.  Identification of lysine succinylation as a new post-translational modification.

Authors:  Zhihong Zhang; Minjia Tan; Zhongyu Xie; Lunzhi Dai; Yue Chen; Yingming Zhao
Journal:  Nat Chem Biol       Date:  2010-12-12       Impact factor: 15.040

4.  The transcription factor snail mediates epithelial to mesenchymal transitions by repression of estrogen receptor-alpha.

Authors:  Archana Dhasarathy; Masahiro Kajita; Paul A Wade
Journal:  Mol Endocrinol       Date:  2007-08-30

5.  SAHA, an HDAC inhibitor, synergizes with tacrolimus to prevent murine cardiac allograft rejection.

Authors:  Xin Zhang; Shu Han; Yindong Kang; Meng Guo; Shanjuan Hong; Fang Liu; Shangxi Fu; Liming Wang; Quan-Xing Wang
Journal:  Cell Mol Immunol       Date:  2012-08-27       Impact factor: 11.530

6.  Endometriosis is characterized by a distinct pattern of histone 3 and histone 4 lysine modifications.

Authors:  Janice B Monteiro; Maricarmen Colón-Díaz; Miosotis García; Sylvia Gutierrez; Mariano Colón; Edward Seto; Joaquín Laboy; Idhaliz Flores
Journal:  Reprod Sci       Date:  2013-07-30       Impact factor: 3.060

Review 7.  Evaluating epigenetic landmarks in the brain of multiple sclerosis patients: a contribution to the current debate on disease pathogenesis.

Authors:  Patrizia Casaccia-Bonnefil; Giovanna Pandozy; Fabrizio Mastronardi
Journal:  Prog Neurobiol       Date:  2008-09-26       Impact factor: 11.685

8.  Identification and verification of lysine propionylation and butyrylation in yeast core histones using PTMap software.

Authors:  Kai Zhang; Yue Chen; Zhihong Zhang; Yingming Zhao
Journal:  J Proteome Res       Date:  2009-02       Impact factor: 4.466

9.  Unbiased proteomic screen for binding proteins to modified lysines on histone H3.

Authors:  Doug W Chan; Yi Wang; Meng Wu; Jiemin Wong; Jun Qin; Yingming Zhao
Journal:  Proteomics       Date:  2009-05       Impact factor: 3.984

10.  Squamocin modulates histone H3 phosphorylation levels and induces G1 phase arrest and apoptosis in cancer cells.

Authors:  Chien-Chih Lee; Yi-Hsiung Lin; Wen-Hsin Chang; Pei-Chin Lin; Yang-Chang Wu; Jan-Gowth Chang
Journal:  BMC Cancer       Date:  2011-02-08       Impact factor: 4.430
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