Literature DB >> 17393442

Liver X receptor is a therapeutic target in collagen-induced arthritis.

Subba R Chintalacharuvu1, George E Sandusky, Thomas P Burris, Glenna C Burmer, Sunil Nagpal.   

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Year:  2007        PMID： 17393442     DOI： 10.1002/art.22528

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN： 0004-3591


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  15 in total

1.  Activation of liver X receptors suppresses inflammatory gene expressions and transcriptional corepressor clearance in rheumatoid arthritis fibroblast like synoviocytes.

Authors:  Chong-Hyeon Yoon; Yong-Jin Kwon; Sang-Won Lee; Yong-Beom Park; Soo-Kon Lee; Min-Chan Park
Journal:  J Clin Immunol       Date:  2012-09-19       Impact factor: 8.317

2.  Increased synovial expression of nuclear receptors correlates with protection in pristane-induced arthritis: a possible novel genetically regulated homeostatic mechanism.

Authors:  Max Brenner; Carl P Linge; Wentian Li; Pércio S Gulko
Journal:  Arthritis Rheum       Date:  2011-10

Review 3.  Regulation of Adaptive Immunity in Health and Disease by Cholesterol Metabolism.

Authors:  Michael B Fessler
Journal:  Curr Allergy Asthma Rep       Date:  2015-08       Impact factor: 4.806

4.  Activation of liver X receptor (LXR) inhibits receptor activator of nuclear factor κB ligand (RANKL)-induced osteoclast differentiation in an LXRβ-dependent mechanism.

Authors:  Kirsten M Robertson Remen; Petra Henning; Ulf H Lerner; Jan-Åke Gustafsson; Göran Andersson
Journal:  J Biol Chem       Date:  2011-07-22       Impact factor: 5.157

5.  Tofacitinib restores the inhibition of reverse cholesterol transport induced by inflammation: understanding the lipid paradox associated with rheumatoid arthritis.

Authors:  S Pérez-Baos; J I Barrasa; P Gratal; A Larrañaga-Vera; I Prieto-Potin; G Herrero-Beaumont; R Largo
Journal:  Br J Pharmacol       Date:  2017-08-03       Impact factor: 8.739

6.  LXR modulation blocks prostaglandin E2 production and matrix degradation in cartilage and alleviates pain in a rat osteoarthritis model.

Authors:  Ning Li; Moisés A Rivéra-Bermúdez; Mei Zhang; Julio Tejada; Sonya S Glasson; Lisa A Collins-Racie; Edward R Lavallie; Yihe Wang; Ken C N Chang; Sunil Nagpal; Elisabeth A Morris; Carl R Flannery; Zhiyong Yang
Journal:  Proc Natl Acad Sci U S A       Date:  2010-02-03       Impact factor: 11.205

7.  Liver X receptor regulates rheumatoid arthritis fibroblast-like synoviocyte invasiveness, matrix metalloproteinase 2 activation, interleukin-6 and CXCL10.

Authors:  Teresina Laragione; Pércio S Gulko
Journal:  Mol Med       Date:  2012-09-07       Impact factor: 6.354

8.  Liver X receptor alpha (LXRalpha) as a therapeutic target in chronic lymphocytic leukemia (CLL).

Authors:  Kent W Christopherson; Alan Landay
Journal:  J Leukoc Biol       Date:  2009-11       Impact factor: 4.962

9.  The arthritis severity locus Cia5a regulates the expression of inflammatory mediators including Syk pathway genes and proteases in pristane-induced arthritis.

Authors:  Max Brenner; Pércio S Gulko
Journal:  BMC Genomics       Date:  2012-12-19       Impact factor: 3.969

10.  Activation of liver X receptor alleviates ocular inflammation in experimental autoimmune uveitis.

Authors:  Hongxia Yang; Shijie Zheng; Yiguo Qiu; Yan Yang; Chaokui Wang; Peizeng Yang; Qiuhong Li; Bo Lei
Journal:  Invest Ophthalmol Vis Sci       Date:  2014-04-28       Impact factor: 4.799
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