Literature DB >> 17393062

Characterization of A7r5 cell line transfected in a stable form by hSSAO/VAP-1 gene (A7r5 hSSAO/VAP-1 cell line).

M Solé1, M Hernandez, M Boada, M Unzeta.   

Abstract

A smooth muscle cell line (A7r5) was stably transfected with the human SSAO/VAP-1 (hSSAO/VAP-1) gene. The expressed protein was located solely in the membrane fraction of the cell. However it was also shown to be released into the cell-culture medium. Both the membrane-bound and released, soluble, forms had SSAO enzyme activity. Although MAO-A is present in wild-type A7r5 cells, it was undetectable in the transfected cells.

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Year:  2007        PMID： 17393062     DOI： 10.1007/s00702-007-0685-9

Source DB:  PubMed          Journal:  J Neural Transm (Vienna)        ISSN： 0300-9564            Impact factor:   3.575


  17 in total

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2.  RADIOISOTOPIC ASSAY FOR MONOAMINE OXIDASE DETERMINATIONS IN HUMAN PLASMA.

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Authors:  D H Fitzgerald; K F Tipton; G A Lyles
Journal:  J Neural Transm Suppl       Date:  1998

Review 4.  Regulation of differentiation of vascular smooth muscle cells.

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Journal:  Physiol Rev       Date:  1995-07       Impact factor: 37.312

5.  Contribution of serum and cellular semicarbazide-sensitive amine oxidase to amine metabolism and cardiovascular toxicity.

Authors:  D J Conklin; S D Langford; P J Boor
Journal:  Toxicol Sci       Date:  1998-12       Impact factor: 4.849

6.  Role of semicarbazide-sensitive amine oxidase on glucose transport and GLUT4 recruitment to the cell surface in adipose cells.

Authors:  G Enrique-Tarancón; L Marti; N Morin; J M Lizcano; M Unzeta; L Sevilla; M Camps; M Palacín; X Testar; C Carpéné; A Zorzano
Journal:  J Biol Chem       Date:  1998-04-03       Impact factor: 5.157

7.  Semicarbazide sensitive amine oxidase overexpression has dual consequences: insulin mimicry and diabetes-like complications.

Authors:  Craig M Stolen; Rami Madanat; Luc Marti; Seppo Kari; Gennady G Yegutkin; Hannu Sariola; Antonio Zorzano; Sirpa Jalkanen
Journal:  FASEB J       Date:  2004-02-20       Impact factor: 5.191

8.  Origins of serum semicarbazide-sensitive amine oxidase.

Authors:  Craig M Stolen; Gennady G Yegutkin; Riikka Kurkijärvi; Petri Bono; Kari Alitalo; Sirpa Jalkanen
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9.  Adipocytes release a soluble form of VAP-1/SSAO by a metalloprotease-dependent process and in a regulated manner.

Authors:  A Abella; S García-Vicente; N Viguerie; A Ros-Baró; M Camps; M Palacín; A Zorzano; L Marti
Journal:  Diabetologia       Date:  2004-02-13       Impact factor: 10.122

10.  Cultured rat vascular smooth muscle cells are resistant to methylamine toxicity: no correlation to semicarbazide-sensitive amine oxidase.

Authors:  S D Langford; M B Trent; P J Boor
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  4 in total

1.  Arterial vascular cell line expressing SSAO: a new tool to study the pathophysiology of vascular amine oxidases.

Authors:  Kaleem Ullah; Bingjie Xie; Javed Iqbal; Aamir Rasool; Hong Qing; Yulin Deng
Journal:  J Neural Transm (Vienna)       Date:  2013-04-02       Impact factor: 3.575

2.  Protective effect of the multitarget compound DPH-4 on human SSAO/VAP-1-expressing hCMEC/D3 cells under oxygen-glucose deprivation conditions: an in vitro experimental model of cerebral ischaemia.

Authors:  P Sun; G Esteban; T Inokuchi; J Marco-Contelles; B B Weksler; I A Romero; P O Couraud; M Unzeta; M Solé
Journal:  Br J Pharmacol       Date:  2015-10-27       Impact factor: 8.739

3.  Increased atherosclerotic plaque in AOC3 knock-out in ApoE-/- mice and characterization of AOC3 in atherosclerotic human coronary arteries.

Authors:  Anna Filip; Soraya Taleb; Rümeyza Bascetin; Mohammad Jahangiri; Matthieu Bardin; Cindy Lerognon; Bruno Fève; Patrick Lacolley; Sirpa Jalkanen; Nathalie Mercier
Journal:  Front Cardiovasc Med       Date:  2022-09-13

Review 4.  SSAO/VAP-1 in Cerebrovascular Disorders: A Potential Therapeutic Target for Stroke and Alzheimer's Disease.

Authors:  Mercedes Unzeta; Mar Hernàndez-Guillamon; Ping Sun; Montse Solé
Journal:  Int J Mol Sci       Date:  2021-03-25       Impact factor: 5.923
  4 in total

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