INTRODUCTION: Colorectal cancer is the second leading cause of cancer-related death in western countries. The objective of this systematic review was to show that laparoscopic-assisted colon resection for cancer is not inferior to open colectomy with respect to cancer survival and perioperative outcomes. METHOD: We performed a comprehensive literature review. Inclusion criteria were adults aged over 16 years with a colon resection for documented colon cancer and randomized controlled trials with laparoscopic- assisted or open resections. We excluded studies that did not document colon cancer recurrence in their article. We assessed data extraction and study quality and performed a quantitative data analysis. RESULTS: Six published and 4 unpublished studies fulfilled our inclusion criteria, with a total of 1262 patients. All primary and secondary outcomes showed good homogeneity, except for morbidity, which was described heterogeneously between the studies. There was no disadvantage to laparoscopic colon resection in any of these primary and secondary outcomes, compared with the conventional open technique. CONCLUSION: The results of this study suggest that, although there is no definitive answer, present evidence indicates that laparoscopic colon cancer resection is as safe and efficacious as the conventional open technique.
INTRODUCTION:Colorectal cancer is the second leading cause of cancer-related death in western countries. The objective of this systematic review was to show that laparoscopic-assisted colon resection for cancer is not inferior to open colectomy with respect to cancer survival and perioperative outcomes. METHOD: We performed a comprehensive literature review. Inclusion criteria were adults aged over 16 years with a colon resection for documented colon cancer and randomized controlled trials with laparoscopic- assisted or open resections. We excluded studies that did not document colon cancer recurrence in their article. We assessed data extraction and study quality and performed a quantitative data analysis. RESULTS: Six published and 4 unpublished studies fulfilled our inclusion criteria, with a total of 1262 patients. All primary and secondary outcomes showed good homogeneity, except for morbidity, which was described heterogeneously between the studies. There was no disadvantage to laparoscopic colon resection in any of these primary and secondary outcomes, compared with the conventional open technique. CONCLUSION: The results of this study suggest that, although there is no definitive answer, present evidence indicates that laparoscopic colon cancer resection is as safe and efficacious as the conventional open technique.
Authors: Sergio Eduardo Alonso Araujo; Afonso Henrique da Silva eSousa; Fábio Guilherme Caserta Marysael de Campos; Angelita Habr-Gama; Rodrigo Blanco Dumarco; Pedro Paulo de Paris Caravatto; Sergio Carlos Nahas; JoséHyppólito da Silva; Desidério Roberto Kiss; Joaquim José Gama-Rodrigues Journal: Rev Hosp Clin Fac Med Sao Paulo Date: 2003-07-22
Authors: Linda Basse; Dorthe Hjort Jakobsen; Linda Bardram; Per Billesbølle; Claus Lund; Torben Mogensen; Jacob Rosenberg; Henrik Kehlet Journal: Ann Surg Date: 2005-03 Impact factor: 12.969
Authors: M L Stead; J M Brown; N Bosanquet; P J Franks; P J Guillou; P Quirke; D Jayne; J R Monson; A V Webb Journal: Crit Rev Oncol Hematol Date: 2000-02 Impact factor: 6.312
Authors: E Lezoche; F Feliciotti; A M Paganini; M Guerrieri; A De Sanctis; S Minervini; R Campagnacci Journal: Surg Endosc Date: 2002-01-09 Impact factor: 4.584
Authors: Antonio M Lacy; Juan C García-Valdecasas; Salvadora Delgado; Antoni Castells; Pilar Taurá; Josep M Piqué; Josep Visa Journal: Lancet Date: 2002-06-29 Impact factor: 79.321
Authors: Heidi Nelson; Daniel J Sargent; H Sam Wieand; James Fleshman; Mehran Anvari; Steven J Stryker; Robert W Beart; Michael Hellinger; Richard Flanagan; Walter Peters; David Ota Journal: N Engl J Med Date: 2004-05-13 Impact factor: 91.245
Authors: Joshua A Waters; Ray Chihara; Jose Moreno; Bruce W Robb; Eric A Wiebke; Virgilio V George Journal: JSLS Date: 2010 Jul-Sep Impact factor: 2.172