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Literature DB >> 1738848

Chondroitin sulfate as a regulator of neuronal patterning in the retina.

Abstract

Highly sulfated proteoglycans are correlated with axon boundaries in the developing central nervous system which suggests that these molecules affect neural pattern formation. In the developing mammalian retina, gradual regression of chondroitin sulfate may help control the onset of ganglion cell differentiation and initial direction of their axons. Changes induced by the removal of chondroitin sulfate from intact retinas in culture confirm the function of chondroitin sulfate in retinal histogenesis.

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Year: 1992 PMID： 1738848 DOI： 10.1126/science.1738848

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

87 in total

1. Neurocan is upregulated in injured brain and in cytokine-treated astrocytes.

Authors: R A Asher; D A Morgenstern; P S Fidler; K H Adcock; A Oohira; J E Braistead; J M Levine; R U Margolis; J H Rogers; J W Fawcett
Journal: J Neurosci Date: 2000-04-01 Impact factor: 6.167

2. DSD-1-proteoglycan is the mouse homolog of phosphacan and displays opposing effects on neurite outgrowth dependent on neuronal lineage.

Authors: J Garwood; O Schnädelbach; A Clement; K Schütte; A Bach; A Faissner
Journal: J Neurosci Date: 1999-05-15 Impact factor: 6.167

3. Roles of the telencephalic cells and their chondroitin sulfate proteoglycans in delimiting an anterior border of the retinal pathway.

Authors: H Ichijo; I Kawabata
Journal: J Neurosci Date: 2001-12-01 Impact factor: 6.167

4. Intact aggrecan and fragments generated by both aggrecanse and metalloproteinase-like activities are present in the developing and adult rat spinal cord and their relative abundance is altered by injury.

Authors: M L Lemons; J D Sandy; D K Anderson; D R Howland
Journal: J Neurosci Date: 2001-07-01 Impact factor: 6.167

5. Schwann cell type V collagen inhibits axonal outgrowth and promotes Schwann cell migration via distinct adhesive activities of the collagen and noncollagen domains.

Authors: M A Chernousov; R C Stahl; D J Carey
Journal: J Neurosci Date: 2001-08-15 Impact factor: 6.167

Chondroitin sulfate as a regulator of neuronal patterning in the retina.

1. Neurocan is upregulated in injured brain and in cytokine-treated astrocytes.

2. DSD-1-proteoglycan is the mouse homolog of phosphacan and displays opposing effects on neurite outgrowth dependent on neuronal lineage.

3. Roles of the telencephalic cells and their chondroitin sulfate proteoglycans in delimiting an anterior border of the retinal pathway.

4. Intact aggrecan and fragments generated by both aggrecanse and metalloproteinase-like activities are present in the developing and adult rat spinal cord and their relative abundance is altered by injury.

5. Schwann cell type V collagen inhibits axonal outgrowth and promotes Schwann cell migration via distinct adhesive activities of the collagen and noncollagen domains.

6. Embryonic neurons adapt to the inhibitory proteoglycan aggrecan by increasing integrin expression.

Review 7. Connecting the eye to the brain: the molecular basis of ganglion cell axon guidance.

8. Prevention of death of axotomized hypoglossal neurones and promotion of regeneration by chitin grafting.

Review 9. Chondroitin sulphate proteoglycans: preventing plasticity or protecting the CNS?

Review 10. Proteoglycans as cues for axonal guidance in formation of retinotectal or retinocollicular projections.