Literature DB >> 17387633

Transcriptional inhibition by a non-histone protein from low mobility group in homologous and heterologous in vitro systems.

Maryam Shahhoseini1, Azra Rabbani-Chadegani.   

Abstract

An acidic non-histone chromosomal protein of low mobility group (LMG) with pI of 5-5.5 and molecular weight of 160 kDa (named LMG160), has been isolated from rat liver nuclei and its inhibitory effect on transcription of DNA in vitro has been detected in a heterologous prokaryotic in vitro transcription system (T7 RNA polymerase) and also confirmed in the homologous cell-free system of rat liver nuclear extract. The results indicate that in the presence of non-histone protein LMG160, in vitro RNA synthesis represses in the both systems, which can suggest a functional role for this non-histone chromosomal protein.

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Year:  2007        PMID： 17387633     DOI： 10.1007/s11033-007-9069-3

Source DB:  PubMed          Journal:  Mol Biol Rep        ISSN： 0301-4851            Impact factor:   2.316


  19 in total

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Journal:  Mol Cell Biol       Date:  1999-08       Impact factor: 4.272

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Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

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Journal:  Biochem Int       Date:  1990-12

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Authors:  S Harish; T Khanam; S Mani; P Rangarajan
Journal:  Nucleic Acids Res       Date:  2001-03-01       Impact factor: 16.971

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Journal:  J Biol Chem       Date:  1975-02-25       Impact factor: 5.157
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  1 in total

1.  Evidence for the structural stability of ribonucleoprotein LMG(160) under ribonuclease-A treatment.

Authors:  Maryam Shahhoseini; Azra Rabbani Chadegani; Sayeh Abdosamadi
Journal:  Mol Cell Biochem       Date:  2008-08-28       Impact factor: 3.396
  1 in total

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