| Literature DB >> 17384994 |
Masamichi Eguchi1, Haruchika Masuda, Takayuki Asahara.
Abstract
Bone marrow-derived endothelial progenitor cells (EPCs) are present in the systemic circulation, are augmented in response to certain cytokines and/or tissue ischemia, and are home to--as well as incorporate into--sites of neovascularization. On the basis of these aspects, EPCs have attractive potential therapeutic applications for cardiovascular ischemic diseases as a novel cell-based strategy, mainly via a vasculogenesis mechanism. This review provides an update of the biology of EPCs, as well as highlighting the potential use of these cells for therapeutic regeneration.Entities:
Mesh:
Year: 2007 PMID: 17384994 DOI: 10.1007/s10157-006-0448-1
Source DB: PubMed Journal: Clin Exp Nephrol ISSN: 1342-1751 Impact factor: 2.801