Literature DB >> 17384953

Management of vestibular schwannomas in young patients-comparison of clinical features and outcome with adult patients.

M Javad Mirzayan1, Venelin M Gerganov, Wolf Lüdemann, Shizuo Oi, Madjid Samii, Amir Samii.   

Abstract

OBJECTS: Vestibular schwannomas (VS) in young patients are rare. They are regarded to have different biological characteristics. Our objective is to analyze a series of such patients, with respect to their clinical presentation, treatment, and outcome and to compare the results to a matched series of adult patients.
MATERIALS AND METHODS: Retrospective analysis of 20 patients under 21 years of age. All patients underwent surgery via the retrosigmoid approach. The analysis included: age, gender, tumor size, clinical, and neurological pre- and postoperative status including cochlear and facial nerve function, and complications. Statistical comparison of the young patient's data with a series of 200 adult patients previously published by the authors.
CONCLUSIONS: The current study demonstrates that the outcome after surgical management in patients harboring VS does not show any significant difference between young and adult patients.

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Mesh:

Year:  2007        PMID: 17384953     DOI: 10.1007/s00381-007-0308-7

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.532


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  3 in total

1.  The role of NF2 gene mutations and pathogenesis-related proteins in sporadic vestibular schwannomas in young individuals.

Authors:  Hongsai Chen; Xiaoman Zhang; Zhihua Zhang; Tao Yang; Zhaoyan Wang; Hao Wu
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2.  Differential NF2 Gene Status in Sporadic Vestibular Schwannomas and its Prognostic Impact on Tumour Growth Patterns.

Authors:  Hongsai Chen; Lu Xue; Hantao Wang; Zhaoyan Wang; Hao Wu
Journal:  Sci Rep       Date:  2017-07-14       Impact factor: 4.379

3.  Gross-total versus near-total resection of large vestibular schwannomas. An institutional experience.

Authors:  Adrian Florian Bălaşa; Corina Ionela Hurghiş; Flaviu Tămaş; Georgiana Mihaela Şerban; Attila Kövecsi; Ioan Alexandru Florian; Rareş Chinezu
Journal:  Rom J Morphol Embryol       Date:  2020 Apr-Jun       Impact factor: 1.033

  3 in total

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