Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Mouse Piwi-interacting RNAs are 2'-O-methylated at their 3' termini.

Literature DB >> 17384647

Mouse Piwi-interacting RNAs are 2'-O-methylated at their 3' termini.

Abstract

Piwi-interacting RNAs (piRNAs) are a novel class of small RNAs that are expressed specifically and abundantly in male germ cells. Here we report that the 3' termini of piRNAs are 2'-O-methylated; this modification may have important implications for the biogenesis and function of piRNAs.

Entities: Gene Species

Mesh：

Substances：

Year: 2007 PMID： 17384647 DOI： 10.1038/nsmb1218

Source DB: PubMed Journal: Nat Struct Mol Biol ISSN： 1545-9985 Impact factor: 15.369

Keyword Cloud
Cited

140 in total

1. A role for transcription from a piRNA cluster in de novo piRNA production.

Authors: Shinpei Kawaoka; Hiroshi Mitsutake; Takashi Kiuchi; Maki Kobayashi; Mayu Yoshikawa; Yutaka Suzuki; Sumio Sugano; Toru Shimada; Jun Kobayashi; Yukihide Tomari; Susumu Katsuma
Journal: RNA Date: 2011-12-22 Impact factor: 4.942

Review 2. Regulation of small RNA stability: methylation and beyond.

Authors: Lijuan Ji; Xuemei Chen
Journal: Cell Res Date: 2012-03-13 Impact factor: 25.617

Review 3. Non-coding RNAs in the plant response to abiotic stress.

Authors: Cecilia Contreras-Cubas; Miguel Palomar; Mario Arteaga-Vázquez; José Luis Reyes; Alejandra A Covarrubias
Journal: Planta Date: 2012-07-04 Impact factor: 4.116

4. Profiling sex-specific piRNAs in zebrafish.

Authors: Xiang Zhou; Zhixiang Zuo; Fang Zhou; Wei Zhao; Yuriko Sakaguchi; Takeo Suzuki; Tsutomu Suzuki; Hanhua Cheng; Rongjia Zhou
Journal: Genetics Date: 2010-09-13 Impact factor: 4.562

5. Kinetic and functional analysis of the small RNA methyltransferase HEN1: the catalytic domain is essential for preferential modification of duplex RNA.

Authors: Giedrius Vilkaitis; Alexandra Plotnikova; Saulius Klimasauskas
Journal: RNA Date: 2010-08-12 Impact factor: 4.942

Mouse Piwi-interacting RNAs are 2'-O-methylated at their 3' termini.

1. A role for transcription from a piRNA cluster in de novo piRNA production.

Review 2. Regulation of small RNA stability: methylation and beyond.

Review 3. Non-coding RNAs in the plant response to abiotic stress.

4. Profiling sex-specific piRNAs in zebrafish.

5. Kinetic and functional analysis of the small RNA methyltransferase HEN1: the catalytic domain is essential for preferential modification of duplex RNA.

6. miR-ID: a novel, circularization-based platform for detection of microRNAs.

7. Selective amplification and sequencing of cyclic phosphate-containing RNAs by the cP-RNA-seq method.

8. Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity.

9. The PIWI proteins SMEDWI-2 and SMEDWI-3 are required for stem cell function and piRNA expression in planarians.

10. piRNA biogenesis during adult spermatogenesis in mice is independent of the ping-pong mechanism.