BACKGROUND: Community based studies of congestive heart failure (HF) are lacking in the Japanese population. METHODS AND RESULTS: To delineate the epidemiological and clinical features of advanced HF in the general Japanese population, hospitalized adult cases of HF in all hospitals within the Ninohe district were registered for 3 years. During the survey period, 190 new onset cases (males n=93; females n=97) and a total of 391 hospitalizations (including repeat admissions) were registered. The prevalence of atrial fibrillation in new HF cases was 56% in males and 45% in females. On the basis of the population of the district, the incidence of hospitalized HF was 96 in males and 92 in females per 100,000 person-years. The percentage of HF patients who were > or =65 years of age was 82% in males and 94% in females. In cases undergoing echocardiography, preserved left ventricular systolic function (left ventricular ejection fraction > or =50%) was observed in 29% of males and 41% of females. There was a significant seasonal variation in HF admissions (Spring 32%; Summer 20%; Autumn 20%; Winter 28%; p<0.01). CONCLUSIONS: In comparison with published results of USA and European community based studies of HF, the present HF cohort showed that: (1) mean age, prevalence of preserved ejection fraction, and trends in seasonal variation were comparable; however (2) the incidence of HF was obviously lower. These epidemiological and clinical characteristics should be taken into consideration when establishing a therapeutic and preventive approach for HF.
BACKGROUND: Community based studies of congestive heart failure (HF) are lacking in the Japanese population. METHODS AND RESULTS: To delineate the epidemiological and clinical features of advanced HF in the general Japanese population, hospitalized adult cases of HF in all hospitals within the Ninohe district were registered for 3 years. During the survey period, 190 new onset cases (males n=93; females n=97) and a total of 391 hospitalizations (including repeat admissions) were registered. The prevalence of atrial fibrillation in new HF cases was 56% in males and 45% in females. On the basis of the population of the district, the incidence of hospitalized HF was 96 in males and 92 in females per 100,000 person-years. The percentage of HF patients who were > or =65 years of age was 82% in males and 94% in females. In cases undergoing echocardiography, preserved left ventricular systolic function (left ventricular ejection fraction > or =50%) was observed in 29% of males and 41% of females. There was a significant seasonal variation in HF admissions (Spring 32%; Summer 20%; Autumn 20%; Winter 28%; p<0.01). CONCLUSIONS: In comparison with published results of USA and European community based studies of HF, the present HF cohort showed that: (1) mean age, prevalence of preserved ejection fraction, and trends in seasonal variation were comparable; however (2) the incidence of HF was obviously lower. These epidemiological and clinical characteristics should be taken into consideration when establishing a therapeutic and preventive approach for HF.
Authors: Gianmarco Lombardi; Giovanni Gambaro; Nicoletta Pertica; Alessandro Naticchia; Matteo Bargagli; Pietro Manuel Ferraro Journal: Environ Health Date: 2021-01-15 Impact factor: 5.984
Authors: Marta Gawrys-Kopczynska; Marek Konop; Klaudia Maksymiuk; Katarzyna Kraszewska; Ladislav Derzsi; Krzysztof Sozanski; Robert Holyst; Marta Pilz; Emilia Samborowska; Leszek Dobrowolski; Kinga Jaworska; Izabella Mogilnicka; Marcin Ufnal Journal: Elife Date: 2020-06-08 Impact factor: 8.140